Expression of ISLR in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

Immunoglobulin superfamily containing leucine-rich repeat

Protein class

Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA050811

GENE INFORMATION
Gene name	ISLR (HGNC Symbol)
Synonyms	HsT17563
Description	Immunoglobulin superfamily containing leucine-rich repeat (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q24.1
Chromosome location (bp)	74173671 - 74176872
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000129009 (version 83.38)
Entrez gene	3671
UniProt	O14498 (UniProt - Evidence at transcript level)
neXtProt	NX_O14498
Antibodypedia	ISLR antibodies

PROTEIN BROWSER

ISLR-001	ISLR-002	ISLR-003	ISLR-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ISLR-001 ENSP00000249842 ENST00000249842	O14498 [Direct mapping] Immunoglobulin superfamily containing leucine-rich repeat protein Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0007155 [cell adhesion] GO:0070062 [extracellular exosome] Show all	428 aa 46 kDa	Yes	0
ISLR-002 ENSP00000378550 ENST00000395118	O14498 [Direct mapping] Immunoglobulin superfamily containing leucine-rich repeat protein Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0007155 [cell adhesion] GO:0070062 [extracellular exosome] Show all	428 aa 46 kDa	Yes	0
ISLR-003 ENSP00000453884 ENST00000559510	H0YN67 [Direct mapping] Immunoglobulin superfamily-containing leucine-rich repeat protein Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	147 aa 16.2 kDa	Yes	0
ISLR-004 ENSP00000453105 ENST00000560862	H0YL90 [Direct mapping] Immunoglobulin superfamily-containing leucine-rich repeat protein Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	183 aa 20.3 kDa	Yes	0