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A subset of tumor cells in few cases of duct carcinomas of breast showed strong nuclear and cytoplasmic staining. Fraction of tumor cells in few cases of glioma, lymphoma, ovarian, endometrial and cervix cancers displayed strong nuclear positivity. Remaining cancer tissues were negative.
GENE INFORMATION
Gene name
FOXJ1 (HGNC Symbol)
Synonyms
FKHL13, HFH-4, HFH4
Description
Forkhead box J1 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the forkhead family of transcription factors. Similar genes in zebrafish and mouse have been shown to regulate the transcription of genes that control the production of motile cilia. The mouse ortholog also functions in the determination of left-right asymmetry. Polymorphisms in this gene are associated with systemic lupus erythematosus and allergic rhinitis.[provided by RefSeq, Sep 2009]