Expression of ART1 in cancer - Summary - The Human Protein Atlas

CANCER ATLAS

Gene description

ADP-ribosyltransferase 1

Protein class

CD markers, Enzymes, Predicted membrane proteins

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA051148

GENE INFORMATION
Gene name	ART1 (HGNC Symbol)
Synonyms	ART2, CD296
Description	ADP-ribosyltransferase 1 (HGNC Symbol)
Entrez gene summary	ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. This gene was previously designated ART2. [provided by RefSeq, Jul 2008]
Chromosome	11
Cytoband	p15.4
Chromosome location (bp)	3645128 - 3664416
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000129744 (version 83.38)
Entrez gene	417
UniProt	P52961 (UniProt - Evidence at transcript level)
neXtProt	NX_P52961
Antibodypedia	ART1 antibodies

PROTEIN BROWSER

ART1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ART1-001 ENSP00000250693 ENST00000250693	P52961 [Direct mapping] GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 Show all	Enzymes ENZYME proteins Transferases CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0003950 [NAD+ ADP-ribosyltransferase activity] GO:0003956 [NAD(P)+-protein-arginine ADP-ribosyltransferase activity] GO:0005886 [plasma membrane] GO:0005887 [integral component of plasma membrane] GO:0006471 [protein ADP-ribosylation] GO:0009986 [cell surface] GO:0031225 [anchored component of membrane] GO:0033017 [sarcoplasmic reticulum membrane] GO:0045087 [innate immune response] Show all	327 aa 36.3 kDa	Yes	1