Cell atlas - KLF16 - The Human Protein Atlas

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KLF16

TISSUE

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CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS MOUSE CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleus

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	KLF16
Gene description	Kruppel-like factor 16
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleus.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (supported)
Mouse	Localized to the Nucleoplasm in mouse cells.

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA052481
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleus.

Main location

Nucleus (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA052481	HEK 293	Nucleus
	HPA052481	MCF7	Nucleus
	HPA052481	U-2 OS	No staining

MOUSE CELLS

Main location

Nucleoplasm

Mouse gene

ENSMUSG00000035397 (version 83)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location
	HPA052481	NIH 3T3	Nucleoplasm

GENE INFORMATION
Gene name	KLF16 (HGNC Symbol)
Synonyms	BTEB4, DRRF, NSLP2
Description	Kruppel-like factor 16 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.3
Chromosome location (bp)	1852399 - 1863568
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000129911 (version 83.38)
Entrez gene	83855
UniProt	Q9BXK1 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BXK1
Antibodypedia	KLF16 antibodies

PROTEIN BROWSER

KLF16-001	KLF16-003	KLF16-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KLF16-001 ENSP00000250916 ENST00000250916	Q9BXK1 [Direct mapping] Krueppel-like factor 16 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000978 [RNA polymerase II core promoter proximal region sequence-specific DNA binding] GO:0001078 [transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0007212 [dopamine receptor signaling pathway] GO:0046872 [metal ion binding] Show all	252 aa 25.4 kDa	No	0
KLF16-003 ENSP00000480570 ENST00000592313	A0A087WWX5 [Direct mapping] Krueppel-like factor 16 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0046872 [metal ion binding] Show all	115 aa 12.3 kDa	No	0
KLF16-201 ENSP00000483701 ENST00000617223	Q9BXK1 [Direct mapping] Krueppel-like factor 16 Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0046872 [metal ion binding] Show all	252 aa 25.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.