Expression of ECSIT in cancer - Summary

CANCER ATLAS

Gene description

ECSIT signalling integrator

Protein class

Predicted intracellular proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA042979

GENE INFORMATION
Gene name	ECSIT (HGNC Symbol)
Synonyms	SITPEC
Description	ECSIT signalling integrator (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.2
Chromosome location (bp)	11505916 - 11529174
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000130159 (version 83.38)
Entrez gene	51295
UniProt	Q9BQ95 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BQ95
Antibodypedia	ECSIT antibodies

PROTEIN BROWSER

ECSIT-001	ECSIT-002	ECSIT-003	ECSIT-004	ECSIT-005	ECSIT-006	ECSIT-007	ECSIT-008	ECSIT-009	ECSIT-014

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ECSIT-001 ENSP00000270517 ENST00000270517	Q9BQ95 [Direct mapping] Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Show all	SignalP predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0016651 [oxidoreductase activity, acting on NAD(P)H] GO:0045087 [innate immune response] GO:0051341 [regulation of oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	431 aa 49.1 kDa	No	0
ECSIT-002 ENSP00000462957 ENST00000585318	J3KTF5 [Direct mapping] Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] Show all	223 aa 26.2 kDa	No	0
ECSIT-003 ENSP00000466559 ENST00000591104	Q9BQ95 [Direct mapping] Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Show all	SignalP predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0016651 [oxidoreductase activity, acting on NAD(P)H] GO:0045087 [innate immune response] GO:0051341 [regulation of oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	296 aa 33.9 kDa	No	0
ECSIT-004 ENSP00000252440 ENST00000252440	Q9BQ95 [Direct mapping] Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Show all	SignalP predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0016651 [oxidoreductase activity, acting on NAD(P)H] GO:0045087 [innate immune response] GO:0051341 [regulation of oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	296 aa 33.2 kDa	No	0
ECSIT-005 ENSP00000412712 ENST00000417981	Q9BQ95 [Direct mapping] Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Show all	SignalP predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0016651 [oxidoreductase activity, acting on NAD(P)H] GO:0045087 [innate immune response] GO:0051341 [regulation of oxidoreductase activity] GO:0055114 [oxidation-reduction process] Show all	217 aa 24.2 kDa	No	0
ECSIT-006 ENSP00000467436 ENST00000590480	K7EPL5 [Direct mapping] Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial Show all	SignalP predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		227 aa 26 kDa	No	0
ECSIT-007 ENSP00000466762 ENST00000592312	K7EN32 [Direct mapping] Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		267 aa 30.2 kDa	No	0
ECSIT-008 ENSP00000468783 ENST00000588998	K7ESM8 [Direct mapping] Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all		82 aa 8.3 kDa	Yes	0
ECSIT-009 ENSP00000465181 ENST00000592665	K7EJI1 [Direct mapping] Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		102 aa 12.3 kDa	No	0
ECSIT-014 ENSP00000466415 ENST00000586149	K7EM98 [Direct mapping] Evolutionarily conserved-signaling intermediate in Toll pathway, mitochondrial Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		25 aa 2.6 kDa	No	0