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Most cancer cells showed moderate to strong cytoplasmic staining that was combined with membranous and/or nuclear positivity in several cases. Hepatocellular carcinomas, most squamous cell carcinomas, melanomas, renal and female genital cancers were weakly stained or negative.
Most cancers showed moderate cytoplasmic positivity. A few cases of gliomas, lymphomas, melanomas, testicular and thyroid cancers showed strong cytoplasmic immunoreactivity.
GENE INFORMATION
Gene name
HIP1R (HGNC Symbol)
Synonyms
FLJ14000, HIP12, HIP3, ILWEQ, KIAA0655
Description
Huntingtin interacting protein 1 related (HGNC Symbol)
O75146 [Direct mapping] Huntingtin-interacting protein 1-related protein
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Predicted intracellular proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)