Expression of EIF3G in cancer - Summary

CANCER ATLAS

Gene description

Eukaryotic translation initiation factor 3, subunit G

Protein class

Plasma proteins, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA041997

GENE INFORMATION
Gene name	EIF3G (HGNC Symbol)
Synonyms	eIF3-delta, eIF3-p44, eIF3g, EIF3S4
Description	Eukaryotic translation initiation factor 3, subunit G (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.2
Chromosome location (bp)	10115017 - 10119918
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000130811 (version 83.38)
Entrez gene	8666
UniProt	O75821 (UniProt - Evidence at protein level)
neXtProt	NX_O75821
Antibodypedia	EIF3G antibodies

PROTEIN BROWSER

EIF3G-001	EIF3G-006	EIF3G-017	EIF3G-018	EIF3G-019

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EIF3G-001 ENSP00000253108 ENST00000253108	O75821 [Direct mapping] Eukaryotic translation initiation factor 3 subunit G Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0001731 [formation of translation preinitiation complex] GO:0003676 [nucleic acid binding] GO:0003743 [translation initiation factor activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0005852 [eukaryotic translation initiation factor 3 complex] GO:0006412 [translation] GO:0006413 [translational initiation] GO:0006446 [regulation of translational initiation] GO:0010467 [gene expression] GO:0016282 [eukaryotic 43S preinitiation complex] GO:0033290 [eukaryotic 48S preinitiation complex] GO:0044267 [cellular protein metabolic process] GO:0044822 [poly(A) RNA binding] GO:0048471 [perinuclear region of cytoplasm] Show all	320 aa 35.6 kDa	No	0
EIF3G-006 ENSP00000466860 ENST00000589454	K7ENA8 [Direct mapping] Eukaryotic translation initiation factor 3 subunit G Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003743 [translation initiation factor activity] GO:0005737 [cytoplasm] GO:0005852 [eukaryotic translation initiation factor 3 complex] GO:0006413 [translational initiation] Show all	289 aa 32.3 kDa	No	0
EIF3G-017 ENSP00000467187 ENST00000593054	K7EP16 [Direct mapping] Eukaryotic translation initiation factor 3 subunit G Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003743 [translation initiation factor activity] GO:0005852 [eukaryotic translation initiation factor 3 complex] GO:0006413 [translational initiation] Show all	118 aa 13.2 kDa	No	0
EIF3G-018 ENSP00000465882 ENST00000588709	K7EL20 [Direct mapping] Eukaryotic translation initiation factor 3 subunit G Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003743 [translation initiation factor activity] GO:0005737 [cytoplasm] GO:0005852 [eukaryotic translation initiation factor 3 complex] GO:0006413 [translational initiation] Show all	263 aa 29.4 kDa	No	0
EIF3G-019 ENSP00000468159 ENST00000587146	K7ER90 [Direct mapping] Eukaryotic translation initiation factor 3 subunit G Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003743 [translation initiation factor activity] GO:0005737 [cytoplasm] GO:0005852 [eukaryotic translation initiation factor 3 complex] GO:0006413 [translational initiation] Show all	227 aa 25.4 kDa	No	0