Expression of PPIL4 in cancer - Summary

CANCER ATLAS

Gene description

Peptidylprolyl isomerase (cyclophilin)-like 4

Protein class

Enzymes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA031600

GENE INFORMATION
Gene name	PPIL4
Synonyms
Description	Peptidylprolyl isomerase (cyclophilin)-like 4 (HGNC Symbol)
Entrez gene summary	This gene is a member of the cyclophilin family of peptidylprolyl isomerases. The cyclophilins are a highly conserved family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. [provided by RefSeq, Jul 2008]
Chromosome	6
Cytoband	q25.1
Chromosome location (bp)	149504733 - 149546038
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000131013 (version 83.38)
Entrez gene	85313
UniProt	Q8WUA2 (UniProt - Evidence at protein level)
neXtProt	NX_Q8WUA2
Antibodypedia	PPIL4 antibodies

PROTEIN BROWSER

PPIL4-001	PPIL4-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PPIL4-001 ENSP00000253329 ENST00000253329	Q8WUA2 [Direct mapping] Peptidyl-prolyl cis-trans isomerase-like 4 Show all	Enzymes ENZYME proteins Isomerase Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000413 [protein peptidyl-prolyl isomerization] GO:0003676 [nucleic acid binding] GO:0003755 [peptidyl-prolyl cis-trans isomerase activity] GO:0005634 [nucleus] GO:0006457 [protein folding] GO:0044822 [poly(A) RNA binding] GO:1901407 [regulation of phosphorylation of RNA polymerase II C-terminal domain] Show all	492 aa 57.2 kDa	No	0
PPIL4-002 ENSP00000344128 ENST00000340881	Q5T4S2 [Direct mapping] Peptidyl-prolyl cis-trans isomerase-like 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000413 [protein peptidyl-prolyl isomerization] GO:0003755 [peptidyl-prolyl cis-trans isomerase activity] GO:1901407 [regulation of phosphorylation of RNA polymerase II C-terminal domain] Show all	127 aa 14.9 kDa	No	0