Expression of TBC1D5 in cancer - Summary

CANCER ATLAS

Gene description

TBC1 domain family, member 5

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA035125	HPA035126

GENE INFORMATION
Gene name	TBC1D5 (HGNC Symbol)
Synonyms	KIAA0210
Description	TBC1 domain family, member 5 (HGNC Symbol)
Entrez gene summary
Chromosome	3
Cytoband	p24.3
Chromosome location (bp)	17157162 - 18444817
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000131374 (version 83.38)
Entrez gene	9779
UniProt	Q92609 (UniProt - Evidence at protein level)
neXtProt	NX_Q92609
Antibodypedia	TBC1D5 antibodies

PROTEIN BROWSER

TBC1D5-001	TBC1D5-002	TBC1D5-004	TBC1D5-005	TBC1D5-011	TBC1D5-016	TBC1D5-018	TBC1D5-019	TBC1D5-020	TBC1D5-022	TBC1D5-023	TBC1D5-024	TBC1D5-029	TBC1D5-030

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TBC1D5-001 ENSP00000253692 ENST00000253692	Q92609 [Direct mapping] TBC1 domain family member 5 B9A6K1 [Target identity:100%; Query identity:100%] TBC1 domain family, member 5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002092 [positive regulation of receptor internalization] GO:0005096 [GTPase activator activity] GO:0005515 [protein binding] GO:0005776 [autophagosome] GO:0010008 [endosome membrane] GO:0010508 [positive regulation of autophagy] GO:0015031 [protein transport] GO:0030122 [AP-2 adaptor complex] GO:0030904 [retromer complex] GO:0035612 [AP-2 adaptor complex binding] GO:0042147 [retrograde transport, endosome to Golgi] GO:0042594 [response to starvation] GO:0043547 [positive regulation of GTPase activity] GO:0098779 [mitophagy in response to mitochondrial depolarization] GO:1990316 [ATG1/UKL1 kinase complex] Show all	795 aa 89 kDa	No	1
TBC1D5-002 ENSP00000398127 ENST00000429383	Q92609 [Direct mapping] TBC1 domain family member 5 B9A6K1 [Target identity:100%; Query identity:100%] TBC1 domain family, member 5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0002092 [positive regulation of receptor internalization] GO:0005096 [GTPase activator activity] GO:0005515 [protein binding] GO:0005776 [autophagosome] GO:0010008 [endosome membrane] GO:0010508 [positive regulation of autophagy] GO:0015031 [protein transport] GO:0030122 [AP-2 adaptor complex] GO:0030904 [retromer complex] GO:0035612 [AP-2 adaptor complex binding] GO:0042147 [retrograde transport, endosome to Golgi] GO:0042594 [response to starvation] GO:0043547 [positive regulation of GTPase activity] GO:0098779 [mitophagy in response to mitochondrial depolarization] GO:1990316 [ATG1/UKL1 kinase complex] Show all	795 aa 89 kDa	No	1
TBC1D5-004 ENSP00000402935 ENST00000446818	Q92609 [Direct mapping] TBC1 domain family member 5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0002092 [positive regulation of receptor internalization] GO:0005096 [GTPase activator activity] GO:0005515 [protein binding] GO:0005776 [autophagosome] GO:0010008 [endosome membrane] GO:0010508 [positive regulation of autophagy] GO:0015031 [protein transport] GO:0030122 [AP-2 adaptor complex] GO:0030904 [retromer complex] GO:0035612 [AP-2 adaptor complex binding] GO:0042147 [retrograde transport, endosome to Golgi] GO:0042594 [response to starvation] GO:0043547 [positive regulation of GTPase activity] GO:0098779 [mitophagy in response to mitochondrial depolarization] GO:1990316 [ATG1/UKL1 kinase complex] Show all	817 aa 91.2 kDa	No	1
TBC1D5-005 ENSP00000411925 ENST00000429924	C9J3F6 [Direct mapping] TBC1 domain family member 5 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all		593 aa 67.5 kDa	No	1
TBC1D5-011 ENSP00000410596 ENST00000445294	C9J397 [Direct mapping] TBC1 domain family member 5 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		129 aa 15.1 kDa	No	0
TBC1D5-016 ENSP00000399967 ENST00000425944	C9JWX0 [Direct mapping] TBC1 domain family member 5 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		140 aa 16.3 kDa	No	0
TBC1D5-018 ENSP00000415379 ENST00000446863	C9JED7 [Direct mapping] TBC1 domain family member 5 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		79 aa 9 kDa	No	0
TBC1D5-019 ENSP00000387395 ENST00000428355	C9JW04 [Direct mapping] TBC1 domain family member 5 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		143 aa 16.6 kDa	No	0
TBC1D5-020 ENSP00000396239 ENST00000415814	C9JDR8 [Direct mapping] TBC1 domain family member 5 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		183 aa 21.6 kDa	No	0
TBC1D5-022 ENSP00000414159 ENST00000434420	C9JNM0 [Direct mapping] TBC1 domain family member 5 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		74 aa 8.5 kDa	No	0
TBC1D5-023 ENSP00000396850 ENST00000444471	C9JIU4 [Direct mapping] TBC1 domain family member 5 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		32 aa 3.6 kDa	No	0
TBC1D5-024 ENSP00000408603 ENST00000433533	C9JMP7 [Direct mapping] TBC1 domain family member 5 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		30 aa 3.5 kDa	No	0
TBC1D5-029 ENSP00000393882 ENST00000414349	C9K0P2 [Direct mapping] TBC1 domain family member 5 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		110 aa 12.8 kDa	No	0
TBC1D5-030 ENSP00000424998 ENST00000507877	F2Z3C3 [Direct mapping] TBC1 domain family member 5 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		88 aa 10.1 kDa	No	0