Expression of LRRC4B in cancer - Summary

CANCER ATLAS

Gene description

Leucine rich repeat containing 4B

Protein class

Predicted membrane proteins, Predicted secreted proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA058986

GENE INFORMATION
Gene name	LRRC4B (HGNC Symbol)
Synonyms	DKFZp761A179, HSM, LRIG4
Description	Leucine rich repeat containing 4B (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	q13.33
Chromosome location (bp)	50516892 - 50568045
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000131409 (version 83.38)
Entrez gene	94030
UniProt	Q9NT99 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9NT99
Antibodypedia	LRRC4B antibodies

PROTEIN BROWSER

LRRC4B-001	LRRC4B-002	LRRC4B-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LRRC4B-001 ENSP00000471502 ENST00000599957	Q9NT99 [Direct mapping] Leucine-rich repeat-containing protein 4B A0A024R4I8 [Target identity:100%; Query identity:100%] HCG1641511, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005102 [receptor binding] GO:0005515 [protein binding] GO:0016021 [integral component of membrane] GO:0030054 [cell junction] GO:0042734 [presynaptic membrane] GO:0044300 [cerebellar mossy fiber] GO:0051965 [positive regulation of synapse assembly] Show all	713 aa 76.4 kDa	Yes	1
LRRC4B-002 ENSP00000472528 ENST00000600381	M0R2G0 [Direct mapping] Leucine-rich repeat-containing protein 4B Show all	THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	238 aa 26.1 kDa	Yes	0
LRRC4B-201 ENSP00000373853 ENST00000389201	Q9NT99 [Direct mapping] Leucine-rich repeat-containing protein 4B A0A024R4I8 [Target identity:100%; Query identity:100%] HCG1641511, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0016021 [integral component of membrane] GO:0030054 [cell junction] GO:0042734 [presynaptic membrane] GO:0051965 [positive regulation of synapse assembly] Show all	713 aa 76.4 kDa	Yes	1