Cell atlas - PDLIM4 - The Human Protein Atlas

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PDLIM4

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Actin filaments
	Cytosol

Human cell
	Actin Filaments
	Cytosol

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GENERAL INFORMATION
Gene name	PDLIM4
Gene description	PDZ and LIM domain 4
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol & actin filaments.
RNA cell category	Cell line enhanced (HaCaT)
Protein evidence	Evidence at protein level
Main location	Localized to the Actin filaments (approved), Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA011912
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (HaCaT) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol & actin filaments.

Main location

Actin filaments (approved), Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA011912	U-2 OS	Actin filaments
	HPA011912	U-251 MG	Cytosol

GENE INFORMATION
Gene name	PDLIM4 (HGNC Symbol)
Synonyms	RIL
Description	PDZ and LIM domain 4 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein which may be involved in bone development. Mutations in this gene are associated with susceptibility to osteoporosis. [provided by RefSeq, Nov 2009]
Chromosome	5
Cytoband	q31.1
Chromosome location (bp)	132257671 - 132273454
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000131435 (version 83.38)
Entrez gene	8572
UniProt	P50479 (UniProt - Evidence at protein level)
neXtProt	NX_P50479
Antibodypedia	PDLIM4 antibodies

PROTEIN BROWSER

PDLIM4-001	PDLIM4-002	PDLIM4-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PDLIM4-001 ENSP00000253754 ENST00000253754	P50479 [Direct mapping] PDZ and LIM domain protein 4 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0008270 [zinc ion binding] Show all	330 aa 35.4 kDa	No	0
PDLIM4-002 ENSP00000368303 ENST00000379018	P50479 [Direct mapping] PDZ and LIM domain protein 4 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0008270 [zinc ion binding] Show all	246 aa 25.9 kDa	No	0
PDLIM4-004 ENSP00000411753 ENST00000418373	C9J542 [Direct mapping] PDZ and LIM domain protein 4 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		121 aa 12.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.