Expression of PEX11B in cancer - Summary

CANCER ATLAS

Gene description

Peroxisomal biogenesis factor 11 beta

Protein class

Disease related genes, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA050104

GENE INFORMATION
Gene name	PEX11B
Synonyms
Description	Peroxisomal biogenesis factor 11 beta (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene facilitates peroxisomal proliferation and interacts with PEX19. The encoded protein is found in the peroxisomal membrane. Several transcript variants, some protein-coding and some not protein-coding, have been found for this gene. [provided by RefSeq, Dec 2012]
Chromosome	1
Cytoband	q21.1
Chromosome location (bp)	145911350 - 145918837
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000131779 (version 83.38)
Entrez gene	8799
UniProt	O96011 (UniProt - Evidence at protein level)
neXtProt	NX_O96011
Antibodypedia	PEX11B antibodies

PROTEIN BROWSER

PEX11B-001	PEX11B-002	PEX11B-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PEX11B-001 ENSP00000358312 ENST00000369306	O96011 [Direct mapping] Peroxisomal membrane protein 11B A0A024R4E7 [Target identity:100%; Query identity:100%] Peroxisomal biogenesis factor 11B, isoform CRA_a Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005777 [peroxisome] GO:0005778 [peroxisomal membrane] GO:0005779 [integral component of peroxisomal membrane] GO:0007031 [peroxisome organization] GO:0007165 [signal transduction] GO:0016020 [membrane] GO:0016559 [peroxisome fission] GO:0042803 [protein homodimerization activity] GO:0043234 [protein complex] GO:0044375 [regulation of peroxisome size] GO:0051260 [protein homooligomerization] GO:0070062 [extracellular exosome] Show all	259 aa 28.4 kDa	No	1
PEX11B-002 ENSP00000414018 ENST00000428634	H7C3V6 [Direct mapping] Peroxisomal membrane protein 11B Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005779 [integral component of peroxisomal membrane] GO:0016559 [peroxisome fission] Show all	81 aa 8.8 kDa	No	1
PEX11B-201 ENSP00000437510 ENST00000537888	O96011 [Direct mapping] Peroxisomal membrane protein 11B Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005777 [peroxisome] GO:0005778 [peroxisomal membrane] GO:0005779 [integral component of peroxisomal membrane] GO:0007031 [peroxisome organization] GO:0007165 [signal transduction] GO:0016020 [membrane] GO:0016559 [peroxisome fission] GO:0042803 [protein homodimerization activity] GO:0043234 [protein complex] GO:0044375 [regulation of peroxisome size] GO:0051260 [protein homooligomerization] GO:0070062 [extracellular exosome] Show all	245 aa 26.7 kDa	No	1