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Fraction of tumor cells in occasional cases of colorectal, pancreatic, endometrial and ovarian cancer exhibited moderate to strong cytoplasmic staining. Remaining malignant tissues were negative.
GENE INFORMATION
Gene name
RAI2
Synonyms
Description
Retinoic acid induced 2 (HGNC Symbol)
Entrez gene summary
Retinoic acid plays a critical role in development, cellular growth, and differentiation. The specific function of this retinoic acid-induced gene has not yet been determined but it may play a role in development. The chromosomal location of this gene designates it to be a candidate for diseases such as Nance-Horan syndrome, sensorineural deafness, non-specific X-linked mental retardation, oral-facial-digital syndrome, and Fried syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
