Cell atlas - LRRC41 - The Human Protein Atlas

GENERAL INFORMATION
Gene name	LRRC41
Gene description	Leucine rich repeat containing 41
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nuclear bodies. In addition localized to the nucleoplasm.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nuclear bodies (approved)
Additional location	In addition localized to the Nucleoplasm (approved)
Mouse	Localized to the Nuclear bodies in mouse cells.

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA051941
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ASSAYS

RNA expression

Human cells

Mouse cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nuclear bodies. In addition localized to the nucleoplasm.

Main location

Nuclear bodies (approved)

Additional location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA051941	HeLa	Nucleoplasm
HPA051941	HeLa	Nuclear bodies
HPA051941	PC-3	Nucleoplasm
HPA051941	PC-3	Nuclear bodies
HPA051941	U-2 OS	Nucleoplasm
HPA051941	U-2 OS	Nuclear bodies

MOUSE CELLS

Main location

Nuclear bodies

Mouse gene

ENSMUSG00000028703 (version 83)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location
	HPA051941	NIH 3T3	Nuclear bodies

GENE INFORMATION
Gene name	LRRC41 (HGNC Symbol)
Synonyms	MUF1
Description	Leucine rich repeat containing 41 (HGNC Symbol)
Entrez gene summary
Chromosome	1
Cytoband
Chromosome location (bp)	46261196 - 46303608
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000132128 (version 83.38)
Entrez gene	10489
UniProt	Q15345 (UniProt - Evidence at protein level)
neXtProt	NX_Q15345
Antibodypedia	LRRC41 antibodies

PROTEIN BROWSER

LRRC41-001	LRRC41-005	LRRC41-006	LRRC41-201	LRRC41-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LRRC41-001 ENSP00000477792 ENST00000617190	Q15345 [Direct mapping] Leucine-rich repeat-containing protein 41 Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0016020 [membrane] GO:0016567 [protein ubiquitination] GO:0042803 [protein homodimerization activity] Show all	812 aa 88.6 kDa	No	0
LRRC41-005 ENSP00000477909 ENST00000496156	A0A087WTI9 [Direct mapping] Leucine-rich repeat-containing protein 41 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		227 aa 25.2 kDa	No	0
LRRC41-006 ENSP00000484752 ENST00000615587	A0A0B4J2G4 [Direct mapping] Leucine-rich repeat-containing protein 41 Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		790 aa 86.2 kDa	No	0
LRRC41-201 ENSP00000343298 ENST00000343304	Q15345 [Direct mapping] Leucine-rich repeat-containing protein 41 Show all	MEMSAT3 predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0016020 [membrane] GO:0016567 [protein ubiquitination] Show all	812 aa 88.6 kDa	No	0
LRRC41-202 ENSP00000484558 ENST00000617760	A0A0C4DH00 [Direct mapping] Leucine-rich repeat-containing protein 41 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		617 aa 67 kDa	No	0