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NUP210

CANCER ATLAS

Gene description

 Nucleoporin 210kDa

Protein class

 Predicted membrane proteins, Transporters

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA066888

GENE INFORMATION

Gene name

 NUP210 (HGNC Symbol)

Synonyms

 FLJ22389, GP210, KIAA0906, POM210

Description

 Nucleoporin 210kDa (HGNC Symbol)

Entrez gene summary

 The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a membrane-spanning glycoprotein that is a major component of the nuclear pore complex. Multiple pseudogenes related to this gene are located on chromosome 3. [provided by RefSeq, Jul 2013]

Chromosome

 3

Cytoband

 p25.1

Chromosome location (bp)

 13316235 - 13420309

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000132182 (version 83.38)

Entrez gene

 23225

UniProt

 Q8TEM1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8TEM1

Antibodypedia

 NUP210 antibodies

PROTEIN BROWSER
NUP210-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
NUP210-001
ENSP00000254508
ENST00000254508
Q8TEM1 [Direct mapping]
Nuclear pore membrane glycoprotein 210
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Transporters
   Transporter channels and pores
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000278 [mitotic cell cycle]
GO:0005635 [nuclear envelope]
GO:0005643 [nuclear pore]
GO:0005789 [endoplasmic reticulum membrane]
GO:0005975 [carbohydrate metabolic process]
GO:0007077 [mitotic nuclear envelope disassembly]
GO:0008033 [tRNA processing]
GO:0008645 [hexose transport]
GO:0010467 [gene expression]
GO:0010827 [regulation of glucose transport]
GO:0015031 [protein transport]
GO:0015758 [glucose transport]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016032 [viral process]
GO:0016925 [protein sumoylation]
GO:0019048 [modulation by virus of host morphology or physiology]
GO:0019054 [modulation by virus of host process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0019221 [cytokine-mediated signaling pathway]
GO:0031047 [gene silencing by RNA]
GO:0031965 [nuclear membrane]
GO:0034605 [cellular response to heat]
GO:0043687 [post-translational protein modification]
GO:0044267 [cellular protein metabolic process]
GO:0044281 [small molecule metabolic process]
GO:0046983 [protein dimerization activity]
GO:0051028 [mRNA transport]
GO:0055085 [transmembrane transport]
GO:1900034 [regulation of cellular response to heat]
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 1887 aa
205.1 kDa 		Yes 1

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.