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LANCL2

GENERAL INFORMATION

Gene name

 LANCL2

Gene description

 LanC lantibiotic synthetase component C-like 2 (bacterial)

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (cerebral cortex)
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in selected tissues, most abundant in smooth muscle and subsets of cells in CNS.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Uncertain based on 2 antibodies.
HPA019711 , HPA029535
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (cerebral cortex)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 LANCL2 (HGNC Symbol)

Synonyms

 GPR69B, TASP

Description

 LanC lantibiotic synthetase component C-like 2 (bacterial) (HGNC Symbol)

Entrez gene summary

Chromosome

 7

Cytoband

 p11.2

Chromosome location (bp)

 55365448 - 55433742

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000132434 (version 83.38)

Entrez gene

 55915

UniProt

 Q9NS86 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NS86

Antibodypedia

 LANCL2 antibodies

PROTEIN BROWSER
LANCL2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
LANCL2-001
ENSP00000254770
ENST00000254770
Q9NS86 [Direct mapping]
LanC-like protein 2
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   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0003824 [catalytic activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005525 [GTP binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0008152 [metabolic process]
GO:0009789 [positive regulation of abscisic acid-activated signaling pathway]
GO:0010314 [phosphatidylinositol-5-phosphate binding]
GO:0030864 [cortical actin cytoskeleton]
GO:0032266 [phosphatidylinositol-3-phosphate binding]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0070273 [phosphatidylinositol-4-phosphate binding]
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 450 aa
50.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.