Expression of PCBD2 in cancer - Summary

CANCER ATLAS

Gene description

Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2

Protein class

Enzymes, Predicted intracellular proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA036428

GENE INFORMATION
Gene name	PCBD2 (HGNC Symbol)
Synonyms	DCOH2, DCOHM
Description	Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 2 (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q31.1
Chromosome location (bp)	134904906 - 135007959
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000132570 (version 83.38)
Entrez gene	84105
UniProt	Q9H0N5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H0N5
Antibodypedia	PCBD2 antibodies

PROTEIN BROWSER

PCBD2-001	PCBD2-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PCBD2-001 ENSP00000254908 ENST00000254908	Q9H0N5 [Direct mapping] Pterin-4-alpha-carbinolamine dehydratase 2 Show all	Enzymes ENZYME proteins Lyases Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0006729 [tetrahydrobiopterin biosynthetic process] GO:0008124 [4-alpha-hydroxytetrahydrobiopterin dehydratase activity] GO:0045893 [positive regulation of transcription, DNA-templated] Show all	130 aa 14.4 kDa	No	0
PCBD2-002 ENSP00000421544 ENST00000512783	Q9H0N5 [Direct mapping] Pterin-4-alpha-carbinolamine dehydratase 2 Show all	Enzymes ENZYME proteins Lyases Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004505 [phenylalanine 4-monooxygenase activity] GO:0005515 [protein binding] GO:0005575 [cellular_component] GO:0005634 [nucleus] GO:0005739 [mitochondrion] GO:0006729 [tetrahydrobiopterin biosynthetic process] GO:0008124 [4-alpha-hydroxytetrahydrobiopterin dehydratase activity] GO:0045893 [positive regulation of transcription, DNA-templated] GO:0051289 [protein homotetramerization] GO:0051291 [protein heterooligomerization] GO:0055114 [oxidation-reduction process] Show all	130 aa 14.4 kDa	No	0