Tissue expression of FCRL2 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	FCRL2
Gene description	Fc receptor-like 2
Protein class	CD markers Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (lymph node, spleen, tonsil, appendix)
GTEx:	Group enriched (spleen, small intestine)
FANTOM5:	Group enriched (appendix, tonsil, spleen)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (lymph node, spleen, tonsil, appendix)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (spleen, small intestine)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (appendix, tonsil, spleen)

GENE INFORMATION
Gene name	FCRL2 (HGNC Symbol)
Synonyms	CD307b, FCRH2, IRTA4, SPAP1
Description	Fc receptor-like 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Apr 2009]
Chromosome	1
Cytoband	q23.1
Chromosome location (bp)	157745733 - 157777132
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000132704 (version 83.38)
Entrez gene	79368
UniProt	Q96LA5 (UniProt - Evidence at protein level)
neXtProt	NX_Q96LA5
Antibodypedia	FCRL2 antibodies

PROTEIN BROWSER

FCRL2-001	FCRL2-003	FCRL2-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FCRL2-001 ENSP00000355157 ENST00000361516	Q96LA5 [Direct mapping] Fc receptor-like protein 2 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005070 [SH3/SH2 adaptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0007267 [cell-cell signaling] GO:0009967 [positive regulation of signal transduction] GO:0016021 [integral component of membrane] Show all	508 aa 55.5 kDa	Yes	1
FCRL2-003 ENSP00000417393 ENST00000469986	Q96LA5 [Direct mapping] Fc receptor-like protein 2 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005070 [SH3/SH2 adaptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0007267 [cell-cell signaling] GO:0009967 [positive regulation of signal transduction] GO:0016021 [integral component of membrane] Show all	192 aa 20.7 kDa	No	1
FCRL2-004 ENSP00000357163 ENST00000368181	Q96LA5 [Direct mapping] Fc receptor-like protein 2 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005070 [SH3/SH2 adaptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0007267 [cell-cell signaling] GO:0009967 [positive regulation of signal transduction] GO:0016021 [integral component of membrane] Show all	202 aa 22.5 kDa	Yes	1