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PPP1R3D

GENERAL INFORMATION

Gene name

 PPP1R3D

Gene description

 Protein phosphatase 1, regulatory subunit 3D

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
FANTOM5:Mixed

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA041146
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Heart muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed

GENE INFORMATION

Gene name

 PPP1R3D (HGNC Symbol)

Synonyms

 PPP1R6

Description

 Protein phosphatase 1, regulatory subunit 3D (HGNC Symbol)

Entrez gene summary

 Phosphorylation of serine and threonine residues in proteins is a crucial step in the regulation of many cellular functions ranging from hormonal regulation to cell division and even short-term memory. The level of phosphorylation is controlled by the opposing actions of protein kinases and protein phosphatases. Protein phosphatase 1 (PP1) is 1 of 4 major serine/threonine-specific protein phosphatases which have been identified in eukaryotic cells. PP1 associates with various regulatory subunits that dictate its subcellular localization and modulate its substrate specificity. Several subunits that target PP1 to glycogen have been identified. This gene encodes a glycogen-targeting subunit of PP1. [provided by RefSeq, Jul 2008]

Chromosome

 20

Cytoband

 q13.33

Chromosome location (bp)

 59936668 - 59940297

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000132825 (version 83.38)

Entrez gene

 5509

UniProt

 O95685 (UniProt - Evidence at protein level)

neXtProt

 NX_O95685

Antibodypedia

 PPP1R3D antibodies

PROTEIN BROWSER
PPP1R3D-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PPP1R3D-001
ENSP00000360035
ENST00000370996
O95685 [Direct mapping]
Protein phosphatase 1 regulatory subunit 3D
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0004721 [phosphoprotein phosphatase activity]
GO:0004722 [protein serine/threonine phosphatase activity]
GO:0005515 [protein binding]
GO:0005977 [glycogen metabolic process]
GO:0005979 [regulation of glycogen biosynthetic process]
GO:0005981 [regulation of glycogen catabolic process]
GO:0006470 [protein dephosphorylation]
GO:0019899 [enzyme binding]
GO:0042587 [glycogen granule]
GO:0043231 [intracellular membrane-bounded organelle]
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 299 aa
32.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.