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MTUS2

GENERAL INFORMATION

Gene name

 MTUS2

Gene description

 Microtubule associated tumor suppressor candidate 2

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (heart muscle, ovary)
GTEx:Tissue enhanced (heart muscle, pituitary gland)
FANTOM5:Tissue enhanced (pituitary gland, heart muscle, cerebellum)

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous cytoplasmic expression in all tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 3 antibodies.
HPA031473 , HPA031474 , HPA031475
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Heart muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (heart muscle, ovary)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (heart muscle, pituitary gland)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (pituitary gland, heart muscle, cerebellum)

GENE INFORMATION

Gene name

 MTUS2 (HGNC Symbol)

Synonyms

 CAZIP, ICIS, KIAA0774, TIP150

Description

 Microtubule associated tumor suppressor candidate 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 13

Cytoband

 q12.3

Chromosome location (bp)

 28820348 - 29505947

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000132938 (version 83.38)

Entrez gene

 23281

UniProt

 Q5JR59 (UniProt - Evidence at protein level)

neXtProt

 NX_Q5JR59

Antibodypedia

 MTUS2 antibodies

PROTEIN BROWSER
MTUS2-001
MTUS2-002
MTUS2-201
MTUS2-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MTUS2-001
ENSP00000370186
ENST00000380808
Q5JR59 [Direct mapping]
Microtubule-associated tumor suppressor candidate 2
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005813 [centrosome]
GO:0005881 [cytoplasmic microtubule]
GO:0008017 [microtubule binding]
GO:0042803 [protein homodimerization activity]
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 348 aa
40.7 kDa 		No 0
MTUS2-002
ENSP00000483729
ENST00000612955
J3KQA9 [Direct mapping]
Microtubule-associated tumor suppressor candidate 2
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Predicted intracellular proteins
Show all
 1379 aa
151.2 kDa 		No 0
MTUS2-201
ENSP00000392057
ENST00000431530
J3KQA9 [Direct mapping]
Microtubule-associated tumor suppressor candidate 2
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
 1379 aa
151.2 kDa 		No 0
MTUS2-202
ENSP00000445403
ENST00000542829
Q5JR59 [Direct mapping]
Microtubule-associated tumor suppressor candidate 2
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005813 [centrosome]
GO:0005881 [cytoplasmic microtubule]
GO:0008017 [microtubule binding]
GO:0042803 [protein homodimerization activity]
Show all
 258 aa
30.1 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.