Tissue expression of XPO4 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	XPO4
Gene description	Exportin 4
Protein class	Plasma proteins Predicted intracellular proteins Transporters
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Mixed
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Mixed
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	XPO4 (HGNC Symbol)
Synonyms	FLJ13046, KIAA1721
Description	Exportin 4 (HGNC Symbol)
Entrez gene summary	XPO4 belongs to a large family of karyopherins (see MIM 602738) that mediate the transport of proteins and other cargo between the nuclear and cytoplasmic compartments (Lipowsky et al., 2000 [PubMed 10944119]).[supplied by OMIM, Mar 2009]
Chromosome	13
Cytoband	q12.11
Chromosome location (bp)	20777329 - 20903048
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000132953 (version 83.38)
Entrez gene	64328
UniProt	Q9C0E2 (UniProt - Evidence at protein level)
neXtProt	NX_Q9C0E2
Antibodypedia	XPO4 antibodies

PROTEIN BROWSER

XPO4-001	XPO4-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
XPO4-001 ENSP00000255305 ENST00000255305	Q9C0E2 [Direct mapping] Exportin-4 Show all	Transporters Transporter channels and pores MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005049 [nuclear export signal receptor activity] GO:0005488 [binding] GO:0005515 [protein binding] GO:0005643 [nuclear pore] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0006611 [protein export from nucleus] GO:0008536 [Ran GTPase binding] GO:0046827 [positive regulation of protein export from nucleus] Show all	1151 aa 130.1 kDa	No	0
XPO4-201 ENSP00000383444 ENST00000400602	F2Z2X4 [Direct mapping] Exportin-4 Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] Show all	1151 aa 130.2 kDa	No	0