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This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. A pseudogene of this gene have been defined on chromosome 6. Alternative splicing results in multiple transcript variants [provided by RefSeq, May 2014]
Q9UPY6 [Direct mapping] Wiskott-Aldrich syndrome protein family member 3 Q5T8P4 [Target identity:100%; Query identity:100%] WAS protein family, member 3, isoform CRA_b; cDNA FLJ76648, highly similar to Homo sapiens WAS protein family, member 3 (WASF3), mRNA
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Predicted intracellular proteins Cancer-related genes Mutated cancer genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)