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SLC41A1

GENERAL INFORMATION

Gene name

 SLC41A1

Gene description

 Solute carrier family 41 (magnesium transporter), member 1

Protein class

 Predicted membrane proteins
Transporters

Predicted localization

 Membrane

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (heart muscle)
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Uncertain based on 1 antibody.
HPA015138
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (heart muscle)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 SLC41A1 (HGNC Symbol)

Synonyms

 MgtE

Description

 Solute carrier family 41 (magnesium transporter), member 1 (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 q32.1

Chromosome location (bp)

 205789093 - 205813748

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000133065 (version 83.38)

Entrez gene

 254428

UniProt

 Q8IVJ1 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q8IVJ1

Antibodypedia

 SLC41A1 antibodies

PROTEIN BROWSER
SLC41A1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SLC41A1-001
ENSP00000356105
ENST00000367137
Q8IVJ1 [Direct mapping]
Solute carrier family 41 member 1
B2RMP2 [Target identity:100%; Query identity:100%]
Solute carrier family 41, member 1; Solute carrier family 41, member 1, isoform CRA_a; cDNA FLJ46190 fis, clone TESTI4005399, highly similar to Homo sapiens solute carrier family 41, member 1 (SLC41A1), mRNA
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Transporters
   Transporter channels and pores
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   9TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
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GO:0005886 [plasma membrane]
GO:0006812 [cation transport]
GO:0008324 [cation transmembrane transporter activity]
GO:0016021 [integral component of membrane]
GO:0055085 [transmembrane transport]
GO:0098655 [cation transmembrane transport]
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 513 aa
54.9 kDa 		No 9

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.