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SEC14L4

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GENERAL INFORMATION

Gene name

 SEC14L4

Gene description

 SEC14-like lipid binding 4

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Localized to the centrosome.

RNA cell category

 Cell line enhanced (BEWO, SiHa, A549)

Protein evidence

 Evidence at protein level

Main location

 Localized to the Centrosome (approved)

DATA RELIABILITY

Reliability score

 Approved based on 1 antibody.
HPA069748
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ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (BEWO, SiHa, A549)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Localized to the centrosome.

Main location

 Centrosome (approved)

 

 

 
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Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA069748 A549 No staining    
HPA069748 SiHa Centrosome
HPA069748 U-2 OS No staining    

GENE INFORMATION

Gene name

 SEC14L4 (HGNC Symbol)

Synonyms

 dJ130H16.5, TAP3

Description

 SEC14-like lipid binding 4 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is highly similar to the protein encoded by the Saccharomyces cerevisiae SEC14 gene. The SEC14 protein is a phophatidylinositol transfer protein that is essential for biogenesis of Golgi-derived transport vesicles, and thus is required for the export of yeast secretory proteins from the Golgi complex. The specific function of this protein has not yet been determined. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2009]

Chromosome

 22

Cytoband

 q12.2

Chromosome location (bp)

 30488913 - 30505711

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000133488 (version 83.38)

Entrez gene

 284904

UniProt

 Q9UDX3 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9UDX3

Antibodypedia

 SEC14L4 antibodies

PROTEIN BROWSER
SEC14L4-001
SEC14L4-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SEC14L4-001
ENSP00000255858
ENST00000255858
Q9UDX3 [Direct mapping]
SEC14-like protein 4
B2RMR2 [Target identity:100%; Query identity:100%]
SEC14-like 4 (S. cerevisiae); SEC14-like 4 (S. cerevisiae), isoform CRA_c; cDNA FLJ36129 fis, clone TESTI2024498, highly similar to SEC14-like protein 4
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   MEMSAT-SVM predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005215 [transporter activity]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0006810 [transport]
GO:0008289 [lipid binding]
GO:0016021 [integral component of membrane]
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 406 aa
46.6 kDa 		No 0
SEC14L4-002
ENSP00000371412
ENST00000381982
Q9UDX3 [Direct mapping]
SEC14-like protein 4
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   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005215 [transporter activity]
GO:0005515 [protein binding]
GO:0005622 [intracellular]
GO:0006810 [transport]
GO:0008289 [lipid binding]
GO:0016021 [integral component of membrane]
Show all
 360 aa
41.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.