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ATP13A3

GENERAL INFORMATION

Gene name

 ATP13A3

Gene description

 ATPase type 13A3

Protein class

 Predicted membrane proteins

Predicted localization

 Membrane

Number of transcripts

 6
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic and nuclear expression in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA029471
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 ATP13A3 (HGNC Symbol)

Synonyms

 AFURS1

Description

 ATPase type 13A3 (HGNC Symbol)

Entrez gene summary

 ATP13A3 is a member of the P-type ATPase family of proteins that transport a variety of cations across membranes. Other P-type ATPases include ATP7B (MIM 606882) and ATP7A (MIM 300011).[supplied by OMIM, Aug 2008]

Chromosome

 3

Cytoband

 q29

Chromosome location (bp)

 194402672 - 194498364

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000133657 (version 83.38)

Entrez gene

 79572

UniProt

 Q9H7F0 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H7F0

Antibodypedia

 ATP13A3 antibodies

PROTEIN BROWSER
ATP13A3-001
ATP13A3-003
ATP13A3-004
ATP13A3-010
ATP13A3-201
ATP13A3-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ATP13A3-001
ENSP00000416508
ENST00000439040
Q9H7F0 [Direct mapping]
Probable cation-transporting ATPase 13A3
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0005524 [ATP binding]
GO:0005887 [integral component of plasma membrane]
GO:0006812 [cation transport]
GO:0006874 [cellular calcium ion homeostasis]
GO:0008152 [metabolic process]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016887 [ATPase activity]
GO:0019829 [cation-transporting ATPase activity]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0046872 [metal ion binding]
GO:0098655 [cation transmembrane transport]
Show all
 1226 aa
138 kDa 		No >9
ATP13A3-003
ENSP00000410767
ENST00000446356
C9JAP7 [Direct mapping]
Probable cation-transporting ATPase 13A3
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006812 [cation transport]
GO:0008152 [metabolic process]
GO:0016021 [integral component of membrane]
GO:0016887 [ATPase activity]
Show all
 47 aa
5.4 kDa 		No 1
ATP13A3-004
ENSP00000406234
ENST00000457986
C9J7Z7 [Direct mapping]
Probable cation-transporting ATPase 13A3
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   1TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0006812 [cation transport]
GO:0008152 [metabolic process]
GO:0016021 [integral component of membrane]
GO:0016887 [ATPase activity]
Show all
 103 aa
12 kDa 		No 1
ATP13A3-010
ENSP00000402550
ENST00000429136
H7C1U7 [Direct mapping]
Probable cation-transporting ATPase 13A3
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   2TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0016021 [integral component of membrane]
Show all
 162 aa
18.9 kDa 		No 2
ATP13A3-201
ENSP00000256031
ENST00000256031
Q9H7F0 [Direct mapping]
Probable cation-transporting ATPase 13A3
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   >9TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0005524 [ATP binding]
GO:0005887 [integral component of plasma membrane]
GO:0006812 [cation transport]
GO:0006874 [cellular calcium ion homeostasis]
GO:0008152 [metabolic process]
GO:0016020 [membrane]
GO:0016021 [integral component of membrane]
GO:0016887 [ATPase activity]
GO:0019829 [cation-transporting ATPase activity]
GO:0043231 [intracellular membrane-bounded organelle]
GO:0046872 [metal ion binding]
GO:0098655 [cation transmembrane transport]
Show all
 1226 aa
138 kDa 		No >9
ATP13A3-202
ENSP00000482200
ENST00000619199
A0A087WYY3 [Direct mapping]
Probable cation-transporting ATPase 13A3
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0005524 [ATP binding]
GO:0006812 [cation transport]
GO:0008152 [metabolic process]
GO:0016021 [integral component of membrane]
GO:0016887 [ATPase activity]
GO:0046872 [metal ion binding]
Show all
 701 aa
77.4 kDa 		No 3

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.