Cell atlas - ADAM20 - The Human Protein Atlas

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ADAM20

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TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	ADAM20
Gene description	ADAM metallopeptidase domain 20
Protein class	Enzymes Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	ADAM20
Synonyms
Description	ADAM metallopeptidase domain 20 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The expression of this gene is testis-specific. [provided by RefSeq, Jul 2008]
Chromosome	14
Cytoband	q24.2
Chromosome location (bp)	70522358 - 70535015
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000134007 (version 83.38)
Entrez gene	8748
UniProt	O43506 (UniProt - Evidence at transcript level)
neXtProt	NX_O43506
Antibodypedia	ADAM20 antibodies

PROTEIN BROWSER

ADAM20-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ADAM20-001 ENSP00000256389 ENST00000256389	O43506 [Direct mapping] Disintegrin and metalloproteinase domain-containing protein 20 Show all	Enzymes Peptidases Metallopeptidases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Show all	GO:0004222 [metalloendopeptidase activity] GO:0005886 [plasma membrane] GO:0006508 [proteolysis] GO:0007338 [single fertilization] GO:0007339 [binding of sperm to zona pellucida] GO:0008237 [metallopeptidase activity] GO:0008270 [zinc ion binding] GO:0016021 [integral component of membrane] GO:0032504 [multicellular organism reproduction] Show all	776 aa 87.1 kDa	No	2

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.