Expression of KIDINS220 in cancer - Summary

CANCER ATLAS

Gene description

Kinase D-interacting substrate, 220kDa

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA014790

GENE INFORMATION
Gene name	KIDINS220 (HGNC Symbol)
Synonyms	ARMS
Description	Kinase D-interacting substrate, 220kDa (HGNC Symbol)
Entrez gene summary
Chromosome	2
Cytoband	p25.1
Chromosome location (bp)	8725278 - 8837630
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000134313 (version 83.38)
Entrez gene	57498
UniProt	Q9ULH0 (UniProt - Evidence at protein level)
neXtProt	NX_Q9ULH0
Antibodypedia	KIDINS220 antibodies

PROTEIN BROWSER

KIDINS220-001	KIDINS220-002	KIDINS220-005	KIDINS220-006	KIDINS220-007	KIDINS220-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KIDINS220-001 ENSP00000256707 ENST00000256707	Q9ULH0 [Direct mapping] Kinase D-interacting substrate of 220 kDa Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000186 [activation of MAPKK activity] GO:0001701 [in utero embryonic development] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005770 [late endosome] GO:0005829 [cytosol] GO:0010976 [positive regulation of neuron projection development] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016482 [cytoplasmic transport] GO:0019887 [protein kinase regulator activity] GO:0030165 [PDZ domain binding] GO:0038180 [nerve growth factor signaling pathway] GO:0043234 [protein complex] GO:0045859 [regulation of protein kinase activity] GO:0048011 [neurotrophin TRK receptor signaling pathway] GO:0048813 [dendrite morphogenesis] GO:1990090 [cellular response to nerve growth factor stimulus] Show all	1771 aa 196.5 kDa	No	4
KIDINS220-002 ENSP00000418974 ENST00000473731	Q9ULH0 [Direct mapping] Kinase D-interacting substrate of 220 kDa Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000186 [activation of MAPKK activity] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005770 [late endosome] GO:0005829 [cytosol] GO:0010976 [positive regulation of neuron projection development] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016482 [cytoplasmic transport] GO:0019887 [protein kinase regulator activity] GO:0030165 [PDZ domain binding] GO:0038180 [nerve growth factor signaling pathway] GO:0043234 [protein complex] GO:0045859 [regulation of protein kinase activity] GO:0048011 [neurotrophin TRK receptor signaling pathway] GO:1990090 [cellular response to nerve growth factor stimulus] Show all	1752 aa 194.6 kDa	No	4
KIDINS220-005 ENSP00000319947 ENST00000319688	Q9ULH0 [Direct mapping] Kinase D-interacting substrate of 220 kDa Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0000186 [activation of MAPKK activity] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005770 [late endosome] GO:0005829 [cytosol] GO:0010976 [positive regulation of neuron projection development] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016482 [cytoplasmic transport] GO:0019887 [protein kinase regulator activity] GO:0030165 [PDZ domain binding] GO:0038180 [nerve growth factor signaling pathway] GO:0043234 [protein complex] GO:0045859 [regulation of protein kinase activity] GO:0048011 [neurotrophin TRK receptor signaling pathway] GO:1990090 [cellular response to nerve growth factor stimulus] Show all	1031 aa 115.3 kDa	No	4
KIDINS220-006 ENSP00000419232 ENST00000459813	H7C584 [Direct mapping] Kinase D-interacting substrate of 220 kDa Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0019887 [protein kinase regulator activity] GO:0030165 [PDZ domain binding] GO:0038180 [nerve growth factor signaling pathway] GO:0045859 [regulation of protein kinase activity] Show all	151 aa 16.5 kDa	No	0
KIDINS220-007 ENSP00000420364 ENST00000496383	H0Y8E4 [Direct mapping] Kinase D-interacting substrate of 220 kDa Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0016021 [integral component of membrane] GO:0019887 [protein kinase regulator activity] GO:0030165 [PDZ domain binding] GO:0038180 [nerve growth factor signaling pathway] GO:0045859 [regulation of protein kinase activity] Show all	1057 aa 118.4 kDa	No	4
KIDINS220-011 ENSP00000419964 ENST00000489024	E9PH70 [Direct mapping] Kinase D-interacting substrate of 220 kDa Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0016021 [integral component of membrane] GO:0019887 [protein kinase regulator activity] GO:0030165 [PDZ domain binding] GO:0038180 [nerve growth factor signaling pathway] GO:0045859 [regulation of protein kinase activity] Show all	1305 aa 145.5 kDa	No	4