Cell atlas - RBM17 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

RBM17

premium

TISSUE

premium

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	RBM17
Gene description	RNA binding motif protein 17
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (supported)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA037478
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (supported)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA037478	A-431	Nucleoplasm
	HPA037478	U-2 OS	Nucleoplasm
	HPA037478	U-251 MG	Nucleoplasm

GENE INFORMATION
Gene name	RBM17 (HGNC Symbol)
Synonyms	MGC14439, SPF45
Description	RNA binding motif protein 17 (HGNC Symbol)
Entrez gene summary	This gene encodes an RNA binding protein. The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 9 and 15. [provided by RefSeq, Mar 2009]
Chromosome	10
Cytoband	p15.1
Chromosome location (bp)	6088987 - 6117457
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000134453 (version 83.38)
Entrez gene	84991
UniProt	Q96I25 (UniProt - Evidence at protein level)
neXtProt	NX_Q96I25
Antibodypedia	RBM17 antibodies

PROTEIN BROWSER

RBM17-003	RBM17-005	RBM17-006	RBM17-007	RBM17-009	RBM17-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RBM17-003 ENSP00000369218 ENST00000379888	Q96I25 [Direct mapping] Splicing factor 45 Q5W009 [Target identity:100%; Query identity:100%] RNA binding motif protein 17, isoform CRA_a; cDNA, FLJ95864 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000380 [alternative mRNA splicing, via spliceosome] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005681 [spliceosomal complex] Show all	401 aa 45 kDa	No	0
RBM17-005 ENSP00000395448 ENST00000437845	Q5W012 [Direct mapping] Splicing factor 45 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0005654 [nucleoplasm] Show all	240 aa 27.1 kDa	No	0
RBM17-006 ENSP00000402303 ENST00000418631	Q5W011 [Direct mapping] Splicing factor 45 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] Show all	212 aa 24.2 kDa	No	0
RBM17-007 ENSP00000408214 ENST00000432931	Q5W010 [Direct mapping] Splicing factor 45 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] Show all	221 aa 25.3 kDa	No	0
RBM17-009 ENSP00000406024 ENST00000447032	H0Y6J6 [Direct mapping] Splicing factor 45 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003676 [nucleic acid binding] Show all	225 aa 25.2 kDa	No	0
RBM17-201 ENSP00000388638 ENST00000446108	Q96I25 [Direct mapping] Splicing factor 45 Q5W009 [Target identity:100%; Query identity:100%] RNA binding motif protein 17, isoform CRA_a; cDNA, FLJ95864 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0000380 [alternative mRNA splicing, via spliceosome] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005681 [spliceosomal complex] Show all	401 aa 45 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.