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RERG

CANCER ATLAS

Gene description

 RAS-like, estrogen-regulated, growth inhibitor

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY
HPA041387

GENE INFORMATION

Gene name

 RERG (HGNC Symbol)

Synonyms

 MGC15754

Description

 RAS-like, estrogen-regulated, growth inhibitor (HGNC Symbol)

Entrez gene summary

 RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation (Finlin et al., 2001 [PubMed 11533059]).[supplied by OMIM, Mar 2009]

Chromosome

 12

Cytoband

 p12.3

Chromosome location (bp)

 15107783 - 15348675

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000134533 (version 83.38)

Entrez gene

 85004

UniProt

 Q96A58 (UniProt - Evidence at protein level)

neXtProt

 NX_Q96A58

Antibodypedia

 RERG antibodies

PROTEIN BROWSER
RERG-001
RERG-002
RERG-004
RERG-005
RERG-007
RERG-009
RERG-010

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RERG-001
ENSP00000256953
ENST00000256953
Q96A58 [Direct mapping]
Ras-related and estrogen-regulated growth inhibitor
A0A024RAT4 [Target identity:100%; Query identity:100%]
RAS-like, estrogen-regulated, growth inhibitor, isoform CRA_a
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0003924 [GTPase activity]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0008285 [negative regulation of cell proliferation]
GO:0009725 [response to hormone]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0019003 [GDP binding]
GO:0030308 [negative regulation of cell growth]
GO:0030331 [estrogen receptor binding]
Show all
 199 aa
22.6 kDa 		No 0
RERG-002
ENSP00000441505
ENST00000538313
Q96A58 [Direct mapping]
Ras-related and estrogen-regulated growth inhibitor
A0A024RAT4 [Target identity:100%; Query identity:100%]
RAS-like, estrogen-regulated, growth inhibitor, isoform CRA_a
Show all
Predicted intracellular proteins
Show all
GO:0003924 [GTPase activity]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0008285 [negative regulation of cell proliferation]
GO:0009725 [response to hormone]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0019003 [GDP binding]
GO:0030308 [negative regulation of cell growth]
GO:0030331 [estrogen receptor binding]
Show all
 199 aa
22.6 kDa 		No 0
RERG-004
ENSP00000444485
ENST00000546331
Q96A58 [Direct mapping]
Ras-related and estrogen-regulated growth inhibitor
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0003924 [GTPase activity]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0008285 [negative regulation of cell proliferation]
GO:0009725 [response to hormone]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0019003 [GDP binding]
GO:0030308 [negative regulation of cell growth]
GO:0030331 [estrogen receptor binding]
Show all
 180 aa
20.3 kDa 		No 0
RERG-005
ENSP00000438280
ENST00000536465
Q96A58 [Direct mapping]
Ras-related and estrogen-regulated growth inhibitor
A0A024RAT4 [Target identity:100%; Query identity:100%]
RAS-like, estrogen-regulated, growth inhibitor, isoform CRA_a
Show all
Predicted intracellular proteins
Show all
GO:0003924 [GTPase activity]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0008285 [negative regulation of cell proliferation]
GO:0009725 [response to hormone]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0019003 [GDP binding]
GO:0030308 [negative regulation of cell growth]
GO:0030331 [estrogen receptor binding]
Show all
 199 aa
22.6 kDa 		No 0
RERG-007
ENSP00000440887
ENST00000393736
F5GYR1 [Direct mapping]
Ras-related and estrogen-regulated growth inhibitor
Show all
Predicted intracellular proteins
Show all
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0007264 [small GTPase mediated signal transduction]
GO:0016020 [membrane]
Show all
 39 aa
4.4 kDa 		No 0
RERG-009
ENSP00000439532
ENST00000545567
F5H252 [Direct mapping]
Ras-related and estrogen-regulated growth inhibitor
Show all
Predicted intracellular proteins
Show all
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0016020 [membrane]
Show all
 113 aa
13.6 kDa 		No 0
RERG-010
ENSP00000441860
ENST00000537647
F5GWE9 [Direct mapping]
Ras-related and estrogen-regulated growth inhibitor
Show all
Predicted intracellular proteins
Show all
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0016020 [membrane]
Show all
 70 aa
7.9 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.