Tissue expression of RNF138 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	RNF138
Gene description	Ring finger protein 138, E3 ubiquitin protein ligase
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Tissue enriched (testis)
FANTOM5:	Tissue enriched (testis)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (testis)

GENE INFORMATION
Gene name	RNF138 (HGNC Symbol)
Synonyms	NARF, STRIN
Description	Ring finger protein 138, E3 ubiquitin protein ligase (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Chromosome	18
Cytoband	q12.1
Chromosome location (bp)	32091855 - 32131561
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000134758 (version 83.38)
Entrez gene	51444
UniProt	Q8WVD3 (UniProt - Evidence at protein level)
neXtProt	NX_Q8WVD3
Antibodypedia	RNF138 antibodies

PROTEIN BROWSER

RNF138-001	RNF138-002	RNF138-004	RNF138-007	RNF138-008	RNF138-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RNF138-001 ENSP00000261593 ENST00000261593	Q8WVD3 [Direct mapping] E3 ubiquitin-protein ligase RNF138 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000209 [protein polyubiquitination] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0008270 [zinc ion binding] GO:0016055 [Wnt signaling pathway] GO:0016874 [ligase activity] GO:0019901 [protein kinase binding] GO:0031624 [ubiquitin conjugating enzyme binding] GO:0032436 [positive regulation of proteasomal ubiquitin-dependent protein catabolic process] GO:0046872 [metal ion binding] GO:0061630 [ubiquitin protein ligase activity] Show all	245 aa 28.2 kDa	No	0
RNF138-002 ENSP00000257190 ENST00000257190	Q8WVD3 [Direct mapping] E3 ubiquitin-protein ligase RNF138 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000209 [protein polyubiquitination] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0008270 [zinc ion binding] GO:0016055 [Wnt signaling pathway] GO:0016874 [ligase activity] GO:0019901 [protein kinase binding] GO:0031624 [ubiquitin conjugating enzyme binding] GO:0032436 [positive regulation of proteasomal ubiquitin-dependent protein catabolic process] GO:0061630 [ubiquitin protein ligase activity] Show all	151 aa 17.3 kDa	No	0
RNF138-004 ENSP00000462165 ENST00000578914	J3KRU4 [Direct mapping] E3 ubiquitin-protein ligase RNF138 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		80 aa 9.4 kDa	No	0
RNF138-007 ENSP00000462498 ENST00000578107	J3KSI2 [Direct mapping] E3 ubiquitin-protein ligase RNF138 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0008270 [zinc ion binding] GO:0046872 [metal ion binding] Show all	108 aa 12.6 kDa	No	0
RNF138-008 ENSP00000463153 ENST00000580499	J3QKM8 [Direct mapping] E3 ubiquitin-protein ligase RNF138 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0008270 [zinc ion binding] GO:0046872 [metal ion binding] Show all	142 aa 16.2 kDa	No	0
RNF138-009 ENSP00000463659 ENST00000577999	J3QLQ3 [Direct mapping] E3 ubiquitin-protein ligase RNF138 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		66 aa 7.4 kDa	No	0