Cell atlas - TCN1 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

TCN1

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	TCN1
Gene description	Transcobalamin I (vitamin B12 binding protein, R binder family)
Protein class	Plasma proteins Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (SiHa, PC-3, CAPAN-2, HaCaT)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SiHa, PC-3, CAPAN-2, HaCaT) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	TCN1 (HGNC Symbol)
Synonyms	TC1, TCI
Description	Transcobalamin I (vitamin B12 binding protein, R binder family) (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This protein is a major constituent of secondary granules in neutrophils and facilitates the transport of cobalamin into cells. [provided by RefSeq, Jul 2008]
Chromosome	11
Cytoband	q12.1
Chromosome location (bp)	59852800 - 59866575
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000134827 (version 83.38)
Entrez gene	6947
UniProt	P20061 (UniProt - Evidence at protein level)
neXtProt	NX_P20061
Antibodypedia	TCN1 antibodies

PROTEIN BROWSER

TCN1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TCN1-001 ENSP00000257264 ENST00000257264	P20061 [Direct mapping] Transcobalamin-1 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0006766 [vitamin metabolic process] GO:0006767 [water-soluble vitamin metabolic process] GO:0006824 [cobalt ion transport] GO:0009235 [cobalamin metabolic process] GO:0015889 [cobalamin transport] GO:0031419 [cobalamin binding] GO:0044281 [small molecule metabolic process] Show all	433 aa 48.2 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.