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RNA cell line category: Cell line enhanced (U-698, SK-MEL-30, SCLC-21H, SH-SY5Y)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.
Cell lines sorted after biological source for establishment.
Cell lines sorted after the cell line category according to Cellosaurus.
Cell lines sorted on descending RNA expression.
Cell lines sorted alphabetically.
GENE INFORMATION
Gene name
HRK (HGNC Symbol)
Synonyms
DP5
Description
Harakiri, BCL2 interacting protein (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the BCL-2 protein family. Members of this family are involved in activating or inhibiting apoptosis. The encoded protein localizes to intracellular membranes. This protein promotes apoptosis by interacting with the apoptotic inhibitors BCL-2 and BCL-X(L) via its BH3 domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0006915 [apoptotic process] GO:0016021 [integral component of membrane] GO:0032464 [positive regulation of protein homooligomerization] GO:0042981 [regulation of apoptotic process] GO:0043065 [positive regulation of apoptotic process] GO:0090200 [positive regulation of release of cytochrome c from mitochondria]
