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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Tissue

Detectable

Cell line

Detectable

Category

Score

Score

Score

Antibodies

Column

 
 
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RINT1
  • TISSUE

  • CELL

  • CANCER

CANCER ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

CANCER ATLAS

Gene description

RAD50 interactor 1

Protein class

Predicted intracellular proteins

Protein evidence

Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA019875

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

A few cases of pancreatic cancers showed strong cytoplasmic immunoreactivity. A majority of malignant melanomas, colorectal, breast, thyroid and liver cancers exhibited weak to moderate cytoplasmic staining. The remaining tumors were mainly negative.

GENE INFORMATION

Gene name

RINT1 (HGNC Symbol)

Synonyms

FLJ11785, RINT-1

Description

RAD50 interactor 1 (HGNC Symbol)

Entrez gene summary

Chromosome

7

Cytoband

q22.3

Chromosome location (bp)

105532085 - 105567677

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000135249 (version 83.38)

Entrez gene

60561

UniProt

Q6NUQ1 (UniProt - Evidence at protein level)

neXtProt

NX_Q6NUQ1

Antibodypedia

RINT1 antibodies

PROTEIN BROWSER

RINT1-001
RINT1-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RINT1-001
ENSP00000257700
ENST00000257700
Q6NUQ1 [Direct mapping]
RAD50-interacting protein 1
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005783 [endoplasmic reticulum]
GO:0005789 [endoplasmic reticulum membrane]
GO:0007049 [cell cycle]
GO:0015031 [protein transport]
GO:0048193 [Golgi vesicle transport]
GO:0060628 [regulation of ER to Golgi vesicle-mediated transport]
GO:0070939 [Dsl1p complex]
GO:1902504 [regulation of signal transduction involved in mitotic G2 DNA damage checkpoint]
Show all
792 aa
90.6 kDa
No 0
RINT1-003
ENSP00000417954
ENST00000493041
C9J5S3 [Direct mapping]
RAD50-interacting protein 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
143 aa
16.3 kDa
No 0

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The Human Protein Atlas project is funded
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