Cell atlas - PRPH - The Human Protein Atlas

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PRPH

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TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	PRPH
Gene description	Peripherin
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Group enriched (AN3-CA, SCLC-21H)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (AN3-CA, SCLC-21H) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	PRPH (HGNC Symbol)
Synonyms	NEF4, PRPH1
Description	Peripherin (HGNC Symbol)
Entrez gene summary	This gene encodes a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis. [provided by RefSeq, Jul 2008]
Chromosome	12
Cytoband	q13.12
Chromosome location (bp)	49293252 - 49298686
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000135406 (version 83.38)
Entrez gene	5630
UniProt	P41219 (UniProt - Evidence at protein level)
neXtProt	NX_P41219
Antibodypedia	PRPH antibodies

PROTEIN BROWSER

PRPH-001	PRPH-002	PRPH-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRPH-001 ENSP00000257860 ENST00000257860	P41219 [Direct mapping] Peripherin Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001750 [photoreceptor outer segment] GO:0005198 [structural molecule activity] GO:0005515 [protein binding] GO:0005882 [intermediate filament] GO:0005883 [neurofilament] GO:0016020 [membrane] GO:0030424 [axon] GO:0042622 [photoreceptor outer segment membrane] GO:0044299 [C-fiber] GO:0045098 [type III intermediate filament] GO:0045104 [intermediate filament cytoskeleton organization] GO:0046982 [protein heterodimerization activity] GO:0070062 [extracellular exosome] Show all	470 aa 53.7 kDa	No	0
PRPH-002 ENSP00000408897 ENST00000451891	F8W835 [Direct mapping] Peripherin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005198 [structural molecule activity] GO:0005882 [intermediate filament] GO:0045098 [type III intermediate filament] Show all	207 aa 24.5 kDa	No	0
PRPH-004 ENSP00000437182 ENST00000532332	H7C5W5 [Direct mapping] Peripherin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005198 [structural molecule activity] GO:0005882 [intermediate filament] GO:0045098 [type III intermediate filament] Show all	200 aa 22.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.