Fields »
ABOUT
HELP
BLOG
MAP7

CANCER ATLAS

Gene description

 Microtubule-associated protein 7

Protein class

 Predicted intracellular proteins

Protein evidence

 Evidence at protein level
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA029712
HPA029713

GENE INFORMATION

Gene name

 MAP7 (HGNC Symbol)

Synonyms

 E-MAP-115

Description

 Microtubule-associated protein 7 (HGNC Symbol)

Entrez gene summary

 The product of this gene is a microtubule-associated protein that is predominantly expressed in cells of epithelial origin. Microtubule-associated proteins are thought to be involved in microtubule dynamics, which is essential for cell polarization and differentiation. This protein has been shown to be able to stabilize microtubules, and may serve to modulate microtubule functions. Studies of the related mouse protein also suggested an essential role in microtubule function required for spermatogenesis. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

Chromosome

 6

Cytoband

 q23.3

Chromosome location (bp)

 136342281 - 136550819

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000135525 (version 83.38)

Entrez gene

 9053

UniProt

 Q14244 (UniProt - Evidence at protein level)

neXtProt

 NX_Q14244

Antibodypedia

 MAP7 antibodies

PROTEIN BROWSER
MAP7-001
MAP7-002
MAP7-003
MAP7-004
MAP7-005
MAP7-201
MAP7-202
MAP7-203
MAP7-204

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
MAP7-001
ENSP00000346581
ENST00000354570
Q14244 [Direct mapping]
Ensconsin
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000226 [microtubule cytoskeleton organization]
GO:0005102 [receptor binding]
GO:0005198 [structural molecule activity]
GO:0005737 [cytoplasm]
GO:0005874 [microtubule]
GO:0005875 [microtubule associated complex]
GO:0006970 [response to osmotic stress]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0015630 [microtubule cytoskeleton]
GO:0016323 [basolateral plasma membrane]
GO:0048471 [perinuclear region of cytoplasm]
GO:0072659 [protein localization to plasma membrane]
Show all
 749 aa
84.1 kDa 		No 0
MAP7-002
ENSP00000400790
ENST00000438100
Q14244 [Direct mapping]
Ensconsin
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000226 [microtubule cytoskeleton organization]
GO:0005102 [receptor binding]
GO:0005198 [structural molecule activity]
GO:0005737 [cytoplasm]
GO:0005874 [microtubule]
GO:0005875 [microtubule associated complex]
GO:0006970 [response to osmotic stress]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0015630 [microtubule cytoskeleton]
GO:0016323 [basolateral plasma membrane]
GO:0048471 [perinuclear region of cytoplasm]
GO:0072659 [protein localization to plasma membrane]
Show all
 734 aa
82.9 kDa 		No 0
MAP7-003
ENSP00000414712
ENST00000454590
Q14244 [Direct mapping]
Ensconsin
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000226 [microtubule cytoskeleton organization]
GO:0005102 [receptor binding]
GO:0005198 [structural molecule activity]
GO:0005737 [cytoplasm]
GO:0005874 [microtubule]
GO:0005875 [microtubule associated complex]
GO:0006970 [response to osmotic stress]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0015630 [microtubule cytoskeleton]
GO:0016323 [basolateral plasma membrane]
GO:0048471 [perinuclear region of cytoplasm]
GO:0072659 [protein localization to plasma membrane]
Show all
 771 aa
87 kDa 		No 0
MAP7-004
ENSP00000445737
ENST00000544465
Q14244 [Direct mapping]
Ensconsin
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000226 [microtubule cytoskeleton organization]
GO:0005102 [receptor binding]
GO:0005198 [structural molecule activity]
GO:0005737 [cytoplasm]
GO:0005874 [microtubule]
GO:0005875 [microtubule associated complex]
GO:0006970 [response to osmotic stress]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0015630 [microtubule cytoskeleton]
GO:0016323 [basolateral plasma membrane]
GO:0048471 [perinuclear region of cytoplasm]
GO:0072659 [protein localization to plasma membrane]
Show all
 734 aa
82.9 kDa 		No 0
MAP7-005
ENSP00000482998
ENST00000611373
Q14244 [Direct mapping]
Ensconsin
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000226 [microtubule cytoskeleton organization]
GO:0005102 [receptor binding]
GO:0005198 [structural molecule activity]
GO:0005737 [cytoplasm]
GO:0005874 [microtubule]
GO:0005875 [microtubule associated complex]
GO:0006970 [response to osmotic stress]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0015630 [microtubule cytoskeleton]
GO:0016323 [basolateral plasma membrane]
GO:0048471 [perinuclear region of cytoplasm]
GO:0072659 [protein localization to plasma membrane]
Show all
 603 aa
66.9 kDa 		No 0
MAP7-201
ENSP00000414879
ENST00000432797
Q14244 [Direct mapping]
Ensconsin
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000226 [microtubule cytoskeleton organization]
GO:0005102 [receptor binding]
GO:0005198 [structural molecule activity]
GO:0005737 [cytoplasm]
GO:0005874 [microtubule]
GO:0005875 [microtubule associated complex]
GO:0006970 [response to osmotic stress]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0015630 [microtubule cytoskeleton]
GO:0016323 [basolateral plasma membrane]
GO:0048471 [perinuclear region of cytoplasm]
GO:0072659 [protein localization to plasma membrane]
Show all
 603 aa
66.9 kDa 		No 0
MAP7-202
ENSP00000483511
ENST00000616617
Q14244 [Direct mapping]
Ensconsin
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000226 [microtubule cytoskeleton organization]
GO:0005102 [receptor binding]
GO:0005198 [structural molecule activity]
GO:0005737 [cytoplasm]
GO:0005874 [microtubule]
GO:0005875 [microtubule associated complex]
GO:0006970 [response to osmotic stress]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0015630 [microtubule cytoskeleton]
GO:0016323 [basolateral plasma membrane]
GO:0048471 [perinuclear region of cytoplasm]
GO:0072659 [protein localization to plasma membrane]
Show all
 655 aa
72.4 kDa 		No 0
MAP7-203
ENSP00000482335
ENST00000617204
A0A087WZ40 [Direct mapping]
Ensconsin
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000226 [microtubule cytoskeleton organization]
GO:0015630 [microtubule cytoskeleton]
Show all
 779 aa
87.8 kDa 		No 0
MAP7-204
ENSP00000482356
ENST00000618822
Q14244 [Direct mapping]
Ensconsin
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000226 [microtubule cytoskeleton organization]
GO:0005102 [receptor binding]
GO:0005198 [structural molecule activity]
GO:0005737 [cytoplasm]
GO:0005874 [microtubule]
GO:0005875 [microtubule associated complex]
GO:0006970 [response to osmotic stress]
GO:0007163 [establishment or maintenance of cell polarity]
GO:0015630 [microtubule cytoskeleton]
GO:0016323 [basolateral plasma membrane]
GO:0048471 [perinuclear region of cytoplasm]
GO:0072659 [protein localization to plasma membrane]
Show all
 712 aa
80 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.