Tissue expression of DYNC1LI2 - Summary

GENERAL INFORMATION
Gene name	DYNC1LI2
Gene description	Dynein, cytoplasmic 1, light intermediate chain 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	DYNC1LI2 (HGNC Symbol)
Synonyms	DNCLI2
Description	Dynein, cytoplasmic 1, light intermediate chain 2 (HGNC Symbol)
Entrez gene summary	Cytoplasmic dynein is a microtubule-associated motor protein (Hughes et al., 1995 [PubMed 7738094]). See DYNC1H1 (MIM 600112) for general information about dyneins.[supplied by OMIM, Mar 2008]
Chromosome	16
Cytoband	q22.1
Chromosome location (bp)	66720893 - 66751798
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000135720 (version 83.38)
Entrez gene	1783
UniProt	O43237 (UniProt - Evidence at protein level)
neXtProt	NX_O43237
Antibodypedia	DYNC1LI2 antibodies

PROTEIN BROWSER

DYNC1LI2-001	DYNC1LI2-003	DYNC1LI2-004	DYNC1LI2-013	DYNC1LI2-014	DYNC1LI2-016

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DYNC1LI2-001 ENSP00000258198 ENST00000258198	O43237 [Direct mapping] Cytoplasmic dynein 1 light intermediate chain 2 A0A024R6Z0 [Target identity:100%; Query identity:100%] Dynein, cytoplasmic 1, light intermediate chain 2, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000226 [microtubule cytoskeleton organization] GO:0003777 [microtubule motor activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005813 [centrosome] GO:0005829 [cytosol] GO:0005868 [cytoplasmic dynein complex] GO:0005874 [microtubule] GO:0006810 [transport] GO:0007018 [microtubule-based movement] GO:0008152 [metabolic process] GO:0016020 [membrane] GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II] GO:0051642 [centrosome localization] Show all	492 aa 54.1 kDa	No	0
DYNC1LI2-003 ENSP00000394289 ENST00000443351	O43237 [Direct mapping] Cytoplasmic dynein 1 light intermediate chain 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003777 [microtubule motor activity] GO:0005524 [ATP binding] GO:0005813 [centrosome] GO:0005829 [cytosol] GO:0005868 [cytoplasmic dynein complex] GO:0005874 [microtubule] GO:0006810 [transport] GO:0007018 [microtubule-based movement] GO:0008152 [metabolic process] GO:0016020 [membrane] GO:0019886 [antigen processing and presentation of exogenous peptide antigen via MHC class II] Show all	415 aa 45 kDa	No	0
DYNC1LI2-004 ENSP00000408566 ENST00000440564	B4E2E0 [Direct mapping] Cytoplasmic dynein 1 light intermediate chain 2; cDNA FLJ54239, highly similar to Cytoplasmic dynein 1 light intermediate chain 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003777 [microtubule motor activity] GO:0005868 [cytoplasmic dynein complex] GO:0007018 [microtubule-based movement] GO:0008152 [metabolic process] Show all	271 aa 30.6 kDa	No	0
DYNC1LI2-013 ENSP00000457707 ENST00000566150	H3BUM4 [Direct mapping] Cytoplasmic dynein 1 light intermediate chain 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003777 [microtubule motor activity] GO:0005868 [cytoplasmic dynein complex] GO:0007018 [microtubule-based movement] GO:0008152 [metabolic process] Show all	186 aa 20.5 kDa	No	0
DYNC1LI2-014 ENSP00000462017 ENST00000569320	J3KRI4 [Direct mapping] Cytoplasmic dynein 1 light intermediate chain 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003777 [microtubule motor activity] GO:0005868 [cytoplasmic dynein complex] GO:0007018 [microtubule-based movement] GO:0008152 [metabolic process] Show all	167 aa 17.8 kDa	No	0
DYNC1LI2-016 ENSP00000462434 ENST00000563628	J3KSD2 [Direct mapping] Cytoplasmic dynein 1 light intermediate chain 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003777 [microtubule motor activity] GO:0005868 [cytoplasmic dynein complex] GO:0007018 [microtubule-based movement] GO:0008152 [metabolic process] Show all	49 aa 5.7 kDa	No	0