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Most malignancies showed moderate cytoplasmic positivity. A few cases of breast, prostate and pancreatic cancers were strongly stained. Malignant gliomas, renal, testicular and skin cancers were generally negative.
A few cases of papillary adenocarcinomas of thyroid, prostate cancers and malignant melanomas exhibited weak to moderate cytoplasmic immunoreactivity. Remaining malignant cells were negative.
Prostate cancers and several malignant melanomas displayed moderate to strong cytoplasmic positivity. A few malignant lymphomas, breast, cervical, and lung cancers were moderately stained. The remaining malignancies were weakly stained or negative.
GENE INFORMATION
Gene name
FAM129A (HGNC Symbol)
Synonyms
C1orf24, GIG39, NIBAN
Description
Family with sequence similarity 129, member A (HGNC Symbol)
Q9BZQ8 [Direct mapping] Protein Niban A0A024R978 [Target identity:100%; Query identity:100%] Chromosome 1 open reading frame 24, isoform CRA_a
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Predicted intracellular proteins Cancer-related genes Candidate cancer biomarkers Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)