Expression of MRPS9 in cancer - Summary

CANCER ATLAS

Gene description

Mitochondrial ribosomal protein S9

Protein class

Plasma proteins, Predicted intracellular proteins, Ribosomal proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA043476	HPA048479

GENE INFORMATION
Gene name	MRPS9 (HGNC Symbol)
Synonyms	MRP-S9, RPMS9, S9mt
Description	Mitochondrial ribosomal protein S9 (HGNC Symbol)
Entrez gene summary	Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. [provided by RefSeq, Jul 2008]
Chromosome	2
Cytoband	q12.1
Chromosome location (bp)	105037983 - 105099960
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000135972 (version 83.38)
Entrez gene	64965
UniProt	P82933 (UniProt - Evidence at protein level)
neXtProt	NX_P82933
Antibodypedia	MRPS9 antibodies

PROTEIN BROWSER

MRPS9-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MRPS9-001 ENSP00000258455 ENST00000258455	P82933 [Direct mapping] 28S ribosomal protein S9, mitochondrial Show all	Ribosomal proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000462 [maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)] GO:0003735 [structural constituent of ribosome] GO:0005515 [protein binding] GO:0005730 [nucleolus] GO:0005739 [mitochondrion] GO:0005743 [mitochondrial inner membrane] GO:0005763 [mitochondrial small ribosomal subunit] GO:0005840 [ribosome] GO:0006412 [translation] GO:0006996 [organelle organization] GO:0032543 [mitochondrial translation] GO:0042769 [DNA damage response, detection of DNA damage] GO:0044822 [poly(A) RNA binding] GO:0070124 [mitochondrial translational initiation] GO:0070125 [mitochondrial translational elongation] GO:0070126 [mitochondrial translational termination] Show all	396 aa 45.8 kDa	No	0