Expression of GPR45 in cancer - Summary

CANCER ATLAS

Gene description

G protein-coupled receptor 45

Protein class

G-protein coupled receptors, Predicted membrane proteins

Protein evidence

Evidence at transcript level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA055940

GENE INFORMATION
Gene name	GPR45 (HGNC Symbol)
Synonyms	PSP24, PSP24A
Description	G protein-coupled receptor 45 (HGNC Symbol)
Entrez gene summary	This intronless gene encodes a member of the G protein-coupled receptor (GPCR) family. Members of this protein family contain seven putative transmembrane domains and may mediate signaling processes to the interior of the cell via activation of heterotrimeric G proteins. This protein may function in the central nervous system. [provided by RefSeq, Jul 2008]
Chromosome	2
Cytoband	q12.1
Chromosome location (bp)	105241743 - 105243049
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000135973 (version 83.38)
Entrez gene	11250
UniProt	Q9Y5Y3 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9Y5Y3
Antibodypedia	GPR45 antibodies

PROTEIN BROWSER

GPR45-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPR45-001 ENSP00000258456 ENST00000258456	Q9Y5Y3 [Direct mapping] Probable G-protein coupled receptor 45 B5B0C1 [Target identity:100%; Query identity:100%] G protein-coupled receptor 45; Orphan GPCR 45 Show all	G-protein coupled receptors GPCRs excl olfactory receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Show all	GO:0004930 [G-protein coupled receptor activity] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0016021 [integral component of membrane] Show all	372 aa 42 kDa	No	7