Tissue expression of CIDEB - Summary - The Human Protein Atlas

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CIDEB

TISSUE

CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	CIDEB
Gene description	Cell death-inducing DFFA-like effector b
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
FANTOM5:	Group enriched (liver, small intestine, colon)

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in several tissues, most abundant in immune cells.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Presumed off target binding observed and disregarded.
Reliability score	Uncertain based on 1 antibody. HPA001272
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

N/A

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (liver, small intestine, colon)

GENE INFORMATION
Gene name	CIDEB
Synonyms
Description	Cell death-inducing DFFA-like effector b (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q12
Chromosome location (bp)	24305096 - 24311430
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000136305 (version 83.38)
Entrez gene	27141
UniProt	Q9UHD4 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UHD4
Antibodypedia	CIDEB antibodies

PROTEIN BROWSER

CIDEB-001	CIDEB-002	CIDEB-003	CIDEB-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CIDEB-001 ENSP00000258807 ENST00000258807	Q9UHD4 [Direct mapping] Cell death activator CIDE-B Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005811 [lipid particle] GO:0005829 [cytosol] GO:0006915 [apoptotic process] GO:0008630 [intrinsic apoptotic signaling pathway in response to DNA damage] GO:0010942 [positive regulation of cell death] GO:0042802 [identical protein binding] GO:0048471 [perinuclear region of cytoplasm] GO:0090200 [positive regulation of release of cytochrome c from mitochondria] GO:0097194 [execution phase of apoptosis] GO:0097202 [activation of cysteine-type endopeptidase activity] Show all	219 aa 24.7 kDa	No	0
CIDEB-002 ENSP00000337731 ENST00000336557	Q9UHD4 [Direct mapping] Cell death activator CIDE-B Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005811 [lipid particle] GO:0005829 [cytosol] GO:0006915 [apoptotic process] GO:0008630 [intrinsic apoptotic signaling pathway in response to DNA damage] GO:0010942 [positive regulation of cell death] GO:0042802 [identical protein binding] GO:0048471 [perinuclear region of cytoplasm] GO:0090200 [positive regulation of release of cytochrome c from mitochondria] GO:0097194 [execution phase of apoptosis] GO:0097202 [activation of cysteine-type endopeptidase activity] Show all	219 aa 24.7 kDa	No	0
CIDEB-003 ENSP00000451089 ENST00000554411	Q9UHD4 [Direct mapping] Cell death activator CIDE-B Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005622 [intracellular] GO:0005811 [lipid particle] GO:0005829 [cytosol] GO:0006915 [apoptotic process] GO:0008630 [intrinsic apoptotic signaling pathway in response to DNA damage] GO:0010942 [positive regulation of cell death] GO:0042802 [identical protein binding] GO:0048471 [perinuclear region of cytoplasm] GO:0090200 [positive regulation of release of cytochrome c from mitochondria] GO:0097194 [execution phase of apoptosis] GO:0097202 [activation of cysteine-type endopeptidase activity] Show all	219 aa 24.7 kDa	No	0
CIDEB-004 ENSP00000451744 ENST00000556756	G3V4E2 [Direct mapping] Cell death activator CIDE-B Show all	Predicted intracellular proteins Show all	GO:0005622 [intracellular] GO:0005811 [lipid particle] GO:0006915 [apoptotic process] Show all	61 aa 6.3 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.