Cell atlas - ALPK3 - The Human Protein Atlas

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ALPK3

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleus

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	ALPK3
Gene description	Alpha-kinase 3
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleus.
RNA cell category	Cell line enhanced (RH-30, LHCN-M2, BEWO, NTERA-2, HUVEC TERT2)
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA026558
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (RH-30, LHCN-M2, BEWO, NTERA-2, HUVEC TERT2) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleus.

Main location

Nucleus (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA026558	A-431	Nucleoplasm
	HPA026558	RH-30	Nucleus
	HPA026558	U-2 OS	Nucleus

GENE INFORMATION
Gene name	ALPK3 (HGNC Symbol)
Synonyms	KIAA1330, MAK, Midori
Description	Alpha-kinase 3 (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q25.3
Chromosome location (bp)	84816680 - 84873482
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000136383 (version 83.38)
Entrez gene	57538
UniProt	Q96L96 (UniProt - Evidence at transcript level)
neXtProt	NX_Q96L96
Antibodypedia	ALPK3 antibodies

PROTEIN BROWSER

ALPK3-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ALPK3-001 ENSP00000258888 ENST00000258888	Q96L96 [Direct mapping] Alpha-protein kinase 3 Show all	Enzymes Kinases Atypical kinases SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004674 [protein serine/threonine kinase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0006468 [protein phosphorylation] GO:0007507 [heart development] GO:0055013 [cardiac muscle cell development] Show all	1907 aa 201.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.