Expression of TM6SF1 in cancer - Summary

CANCER ATLAS

Gene description

Transmembrane 6 superfamily member 1

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA016051	HPA056857

GENE INFORMATION
Gene name	TM6SF1
Synonyms
Description	Transmembrane 6 superfamily member 1 (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q25.2
Chromosome location (bp)	83107407 - 83144854
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000136404 (version 83.38)
Entrez gene	53346
UniProt	Q9BZW5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BZW5
Antibodypedia	TM6SF1 antibodies

PROTEIN BROWSER

TM6SF1-001	TM6SF1-005	TM6SF1-006	TM6SF1-009	TM6SF1-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TM6SF1-001 ENSP00000317000 ENST00000322019	Q9BZW5 [Direct mapping] Transmembrane 6 superfamily member 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0003674 [molecular_function] GO:0005765 [lysosomal membrane] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] Show all	370 aa 41.6 kDa	Yes	8
TM6SF1-005 ENSP00000457477 ENST00000565774	Q9BZW5 [Direct mapping] Transmembrane 6 superfamily member 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 8TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0003674 [molecular_function] GO:0005765 [lysosomal membrane] GO:0008150 [biological_process] GO:0016021 [integral component of membrane] Show all	339 aa 38 kDa	Yes	8
TM6SF1-006 ENSP00000368700 ENST00000379390	Q6P4D7 [Direct mapping] TM6SF1 protein; Transmembrane 6 superfamily member 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	188 aa 20.9 kDa	Yes	5
TM6SF1-009 ENSP00000454275 ENST00000565982	H3BM84 [Direct mapping] Transmembrane 6 superfamily member 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 4TM proteins predicted by MDM Show all	GO:0016021 [integral component of membrane] Show all	166 aa 19.1 kDa	No	4
TM6SF1-010 ENSP00000454416 ENST00000561551	H3BMK0 [Direct mapping] Transmembrane 6 superfamily member 1 Show all	Predicted intracellular proteins Show all		30 aa 3 kDa	No	0