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Moderate to strong cytoplasmic positivity with a granular pattern was observed in most malignant cells. Malignant carcinoids and skin cancers were negative in the majority of cases.
Weak to moderate cytoplasmic positivity with a granular pattern was observed in malignant cells. A few cases of hepatocellular carcinomas were strongly stained. Most skin cancers were negative.
GENE INFORMATION
Gene name
TACO1 (HGNC Symbol)
Synonyms
CCDC44
Description
Translational activator of mitochondrially encoded cytochrome c oxidase I (HGNC Symbol)
Entrez gene summary
This gene encodes a mitochondrial protein that function as a translational activator of mitochondrially-encoded cytochrome c oxidase 1. Mutations in this gene are associated with Leigh syndrome.[provided by RefSeq, Mar 2010]
Q9BSH4 [Direct mapping] Translational activator of cytochrome c oxidase 1
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Phobius predicted secreted proteins Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)