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KAT7

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GENERAL INFORMATION

Gene name

 KAT7

Gene description

 K(lysine) acetyltransferase 7

Protein class

 Enzymes
Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 7
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HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to the nucleoplasm.

RNA cell category

 Expressed in all

Protein evidence

 Evidence at protein level

Main location

 Localized to the Nucleoplasm (supported)

Mouse

 Localized to the Nucleoplasm in mouse cells.

DATA RELIABILITY

Reliability score

 Supported based on 1 antibody.
HPA044470
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ASSAYS
RNA expression
Human cells
Mouse cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to the nucleoplasm.

Main location

 Nucleoplasm (supported)

 

 

 
Toggle channels
Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA044470 A-431 Nucleoplasm
Cytosol
HPA044470 PC-3 Nucleoplasm
HPA044470 U-2 OS Nucleoplasm

MOUSE CELLS

Main location

 Nucleoplasm

Additional location

 Plasma membrane

Mouse gene

 ENSMUSG00000038909 (version 83)

 

 

 
Toggle channels
Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location
HPA044470 NIH 3T3 Nucleoplasm
Plasma membrane

GENE INFORMATION

Gene name

 KAT7 (HGNC Symbol)

Synonyms

 HBO1, HBOA, MYST2, ZC2HC7

Description

 K(lysine) acetyltransferase 7 (HGNC Symbol)

Entrez gene summary

Chromosome

 17

Cytoband

 q21.33

Chromosome location (bp)

 49788555 - 49835030

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000136504 (version 83.38)

Entrez gene

 11143

UniProt

 O95251 (UniProt - Evidence at protein level)

neXtProt

 NX_O95251

Antibodypedia

 KAT7 antibodies

PROTEIN BROWSER
KAT7-001
KAT7-002
KAT7-003
KAT7-004
KAT7-006
KAT7-008
KAT7-014

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
KAT7-001
ENSP00000259021
ENST00000259021
O95251 [Direct mapping]
Histone acetyltransferase KAT7
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000123 [histone acetyltransferase complex]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0004402 [histone acetyltransferase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006260 [DNA replication]
GO:0006325 [chromatin organization]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0016747 [transferase activity, transferring acyl groups other than amino-acyl groups]
GO:0043966 [histone H3 acetylation]
GO:0043981 [histone H4-K5 acetylation]
GO:0043982 [histone H4-K8 acetylation]
GO:0043983 [histone H4-K12 acetylation]
GO:1900182 [positive regulation of protein localization to nucleus]
Show all
 611 aa
70.6 kDa 		No 0
KAT7-002
ENSP00000413415
ENST00000454930
O95251 [Direct mapping]
Histone acetyltransferase KAT7
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000123 [histone acetyltransferase complex]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0004402 [histone acetyltransferase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006260 [DNA replication]
GO:0006325 [chromatin organization]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0016747 [transferase activity, transferring acyl groups other than amino-acyl groups]
GO:0043966 [histone H3 acetylation]
GO:0043981 [histone H4-K5 acetylation]
GO:0043982 [histone H4-K8 acetylation]
GO:0043983 [histone H4-K12 acetylation]
GO:1900182 [positive regulation of protein localization to nucleus]
Show all
 472 aa
55.1 kDa 		No 0
KAT7-003
ENSP00000424577
ENST00000509773
O95251 [Direct mapping]
Histone acetyltransferase KAT7
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000123 [histone acetyltransferase complex]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0004402 [histone acetyltransferase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006260 [DNA replication]
GO:0006325 [chromatin organization]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0016747 [transferase activity, transferring acyl groups other than amino-acyl groups]
GO:0043966 [histone H3 acetylation]
GO:0043981 [histone H4-K5 acetylation]
GO:0043982 [histone H4-K8 acetylation]
GO:0043983 [histone H4-K12 acetylation]
GO:1900182 [positive regulation of protein localization to nucleus]
Show all
 501 aa
58.1 kDa 		No 0
KAT7-004
ENSP00000423385
ENST00000510819
O95251 [Direct mapping]
Histone acetyltransferase KAT7
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000123 [histone acetyltransferase complex]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0004402 [histone acetyltransferase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006260 [DNA replication]
GO:0006325 [chromatin organization]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0016747 [transferase activity, transferring acyl groups other than amino-acyl groups]
GO:0043966 [histone H3 acetylation]
GO:0043981 [histone H4-K5 acetylation]
GO:0043982 [histone H4-K8 acetylation]
GO:0043983 [histone H4-K12 acetylation]
GO:1900182 [positive regulation of protein localization to nucleus]
Show all
 442 aa
51.4 kDa 		No 0
KAT7-006
ENSP00000398961
ENST00000424009
O95251 [Direct mapping]
Histone acetyltransferase KAT7
Show all
Enzymes
   ENZYME proteins
   Transferases
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000123 [histone acetyltransferase complex]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0004402 [histone acetyltransferase activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006260 [DNA replication]
GO:0006325 [chromatin organization]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0016747 [transferase activity, transferring acyl groups other than amino-acyl groups]
GO:0043966 [histone H3 acetylation]
GO:0043981 [histone H4-K5 acetylation]
GO:0043982 [histone H4-K8 acetylation]
GO:0043983 [histone H4-K12 acetylation]
GO:1900182 [positive regulation of protein localization to nucleus]
Show all
 581 aa
66.9 kDa 		No 0
KAT7-008
ENSP00000409477
ENST00000435742
E7EUP3 [Direct mapping]
Histone acetyltransferase
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0004402 [histone acetyltransferase activity]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0008270 [zinc ion binding]
GO:0016573 [histone acetylation]
GO:0016747 [transferase activity, transferring acyl groups other than amino-acyl groups]
Show all
 425 aa
49.9 kDa 		No 0
KAT7-014
ENSP00000421368
ENST00000506533
D6RFZ5 [Direct mapping]
Histone acetyltransferase KAT7
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 16 aa
1.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.