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HLX

GENERAL INFORMATION

Gene name

 HLX

Gene description

 H2.0-like homeobox

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (bone marrow)
GTEx:Mixed
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic and nuclear expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Sub cellular location is contradicted by external data. Pending external verification.

Reliability score

 Uncertain based on 1 antibody.
HPA005968
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (bone marrow)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 HLX (HGNC Symbol)

Synonyms

 HB24, HLX1

Description

 H2.0-like homeobox (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 q41

Chromosome location (bp)

 220879400 - 220885059

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000136630 (version 83.38)

Entrez gene

 3142

UniProt

 Q14774 (UniProt - Evidence at protein level)

neXtProt

 NX_Q14774

Antibodypedia

 HLX antibodies

PROTEIN BROWSER
HLX-001
HLX-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
HLX-001
ENSP00000355870
ENST00000366903
Q14774 [Direct mapping]
H2.0-like homeobox protein
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Predicted intracellular proteins
Transcription factors
   Helix-turn-helix domains
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GO:0001889 [liver development]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0007275 [multicellular organismal development]
GO:0007519 [skeletal muscle tissue development]
GO:0008284 [positive regulation of cell proliferation]
GO:0030154 [cell differentiation]
GO:0043565 [sequence-specific DNA binding]
GO:0045627 [positive regulation of T-helper 1 cell differentiation]
GO:0045629 [negative regulation of T-helper 2 cell differentiation]
GO:0046622 [positive regulation of organ growth]
GO:0048484 [enteric nervous system development]
GO:0048513 [organ development]
GO:0048557 [embryonic digestive tract morphogenesis]
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 488 aa
50.8 kDa 		No 0
HLX-002
ENSP00000408248
ENST00000427693
F8VWZ5 [Direct mapping]
H2.0-like homeobox protein
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Predicted intracellular proteins
Show all
GO:0003677 [DNA binding]
GO:0005634 [nucleus]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0043565 [sequence-specific DNA binding]
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 151 aa
17 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.