Tissue expression of SAP130 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	SAP130
Gene description	Sin3A-associated protein, 130kDa
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	SAP130 (HGNC Symbol)
Synonyms	FLJ12761
Description	Sin3A-associated protein, 130kDa (HGNC Symbol)
Entrez gene summary	SAP130 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).[supplied by OMIM, Mar 2008]
Chromosome	2
Cytoband	q14.3
Chromosome location (bp)	127941217 - 128028120
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000136715 (version 83.38)
Entrez gene	79595
UniProt	Q9H0E3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H0E3
Antibodypedia	SAP130 antibodies

PROTEIN BROWSER

SAP130-001	SAP130-002	SAP130-003	SAP130-004	SAP130-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SAP130-001 ENSP00000259235 ENST00000259235	Q9H0E3 [Direct mapping] Histone deacetylase complex subunit SAP130 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003713 [transcription coactivator activity] GO:0004402 [histone acetyltransferase activity] GO:0005654 [nucleoplasm] GO:0006325 [chromatin organization] GO:0006351 [transcription, DNA-templated] GO:0010467 [gene expression] GO:0030914 [STAGA complex] GO:0040029 [regulation of gene expression, epigenetic] GO:0043966 [histone H3 acetylation] GO:0045814 [negative regulation of gene expression, epigenetic] Show all	1048 aa 110.3 kDa	No	0
SAP130-002 ENSP00000259234 ENST00000259234	H7BXF5 [Direct mapping] Histone deacetylase complex subunit SAP130 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] Show all	1056 aa 111.3 kDa	No	0
SAP130-003 ENSP00000411634 ENST00000424298	C9J683 [Direct mapping] Histone deacetylase complex subunit SAP130 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		262 aa 27 kDa	No	0
SAP130-004 ENSP00000414593 ENST00000450957	C9JTJ5 [Direct mapping] Histone deacetylase complex subunit SAP130 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		144 aa 14.8 kDa	No	0
SAP130-201 ENSP00000350333 ENST00000357702	Q9H0E3 [Direct mapping] Histone deacetylase complex subunit SAP130 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0003713 [transcription coactivator activity] GO:0004402 [histone acetyltransferase activity] GO:0005654 [nucleoplasm] GO:0006325 [chromatin organization] GO:0006351 [transcription, DNA-templated] GO:0010467 [gene expression] GO:0030914 [STAGA complex] GO:0040029 [regulation of gene expression, epigenetic] GO:0043966 [histone H3 acetylation] GO:0045814 [negative regulation of gene expression, epigenetic] Show all	1083 aa 114 kDa	No	0