Tissue expression of KIAA0368 - Summary - The Human Protein Atlas

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KIAA0368

TISSUE

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CELL

CANCER

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	KIAA0368
Gene description	KIAA0368
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression, most abundant in pancreas and stomach.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification. Presumed off target binding observed and disregarded.
Reliability score	Uncertain based on 2 antibodies. HPA021646 , HPA059795
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	KIAA0368 (HGNC Symbol)
Synonyms	ECM29, FLJ22036
Description	KIAA0368 (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	q31.3
Chromosome location (bp)	111360692 - 111484745
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000136813 (version 83.38)
Entrez gene	23392
UniProt	Q5VYK3 (UniProt - Evidence at protein level)
neXtProt	NX_Q5VYK3
Antibodypedia	KIAA0368 antibodies

PROTEIN BROWSER

KIAA0368-001	KIAA0368-002	KIAA0368-004	KIAA0368-005	KIAA0368-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KIAA0368-001 ENSP00000339889 ENST00000338205	Q5VYK3 [Direct mapping] Proteasome-associated protein ECM29 homolog Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000502 [proteasome complex] GO:0003674 [molecular_function] GO:0005488 [binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005769 [early endosome] GO:0005770 [late endosome] GO:0005771 [multivesicular body] GO:0005783 [endoplasmic reticulum] GO:0005793 [endoplasmic reticulum-Golgi intermediate compartment] GO:0005813 [centrosome] GO:0016020 [membrane] GO:0016023 [cytoplasmic membrane-bounded vesicle] GO:0030134 [ER to Golgi transport vesicle] GO:0030139 [endocytic vesicle] GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process] Show all	1839 aa 203.8 kDa	No	0
KIAA0368-002 ENSP00000363504 ENST00000374383	F6XAQ5 [Direct mapping] Proteasome-associated protein ECM29 homolog Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] Show all	142 aa 15.4 kDa	No	0
KIAA0368-004 ENSP00000473402 ENST00000602978	R4GMY3 [Direct mapping] Proteasome-associated protein ECM29 homolog Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		128 aa 14.8 kDa	No	0
KIAA0368-005 ENSP00000473399 ENST00000602447	R4GMY1 [Direct mapping] Proteasome-associated protein ECM29 homolog Show all	MEMSAT3 predicted membrane proteins Phobius predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] Show all	890 aa 98.5 kDa	No	0
KIAA0368-201 ENSP00000259335 ENST00000259335	J3KN16 [Direct mapping] Proteasome-associated protein ECM29 homolog Show all	Phobius predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005488 [binding] Show all	2017 aa 223.7 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.