Cell atlas - ZFP37 - The Human Protein Atlas

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ZFP37

TISSUE

CELL

CANCER

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleus
	Vesicles

Human cell
	Nucleoplasm
	Vesicles

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GENERAL INFORMATION
Gene name	ZFP37
Gene description	ZFP37 zinc finger protein
Protein class	Predicted intracellular proteins Transcription factors
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleus & vesicles.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (approved), Vesicles (approved)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA049112
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleus & vesicles.

Main location

Nucleus (approved), Vesicles (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA049112	RH-30	Nucleus
	HPA049112	RH-30	Vesicles	Intensity
	HPA049112	SiHa	Nucleus
	HPA049112	SiHa	Vesicles
	HPA049112	U-2 OS	Nucleus
	HPA049112	U-2 OS	Vesicles

GENE INFORMATION
Gene name	ZFP37 (HGNC Symbol)
Synonyms	ZNF906
Description	ZFP37 zinc finger protein (HGNC Symbol)
Entrez gene summary	This gene encodes a transcription factor that belongs to a large family of zinc finger proteins. A similar protein in mouse is thought to play a role in regulating the structures of the nucleolus and centromere in neurons. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Chromosome	9
Cytoband	q32
Chromosome location (bp)	113038380 - 113056759
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000136866 (version 83.38)
Entrez gene	7539
UniProt	Q9Y6Q3 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9Y6Q3
Antibodypedia	ZFP37 antibodies

PROTEIN BROWSER

ZFP37-001	ZFP37-002	ZFP37-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZFP37-001 ENSP00000363344 ENST00000374227	Q9Y6Q3 [Direct mapping] Zinc finger protein 37 homolog Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Protein evidence (Kim et al 2014) Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0046872 [metal ion binding] Show all	630 aa 71.2 kDa	No	0
ZFP37-002 ENSP00000452552 ENST00000553380	Q9Y6Q3 [Direct mapping] Zinc finger protein 37 homolog Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0046872 [metal ion binding] Show all	645 aa 72.9 kDa	No	0
ZFP37-003 ENSP00000451310 ENST00000555206	Q9Y6Q3 [Direct mapping] Zinc finger protein 37 homolog Show all	Predicted intracellular proteins Transcription factors Zinc-coordinating DNA-binding domains Show all	GO:0003676 [nucleic acid binding] GO:0003677 [DNA binding] GO:0003700 [transcription factor activity, sequence-specific DNA binding] GO:0005622 [intracellular] GO:0005634 [nucleus] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0008270 [zinc ion binding] GO:0046872 [metal ion binding] Show all	631 aa 71.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.