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Most hepatocellular cancers were moderately or strongly stained. Remaining cancers were negative.
GENE INFORMATION
Gene name
BAAT (HGNC Symbol)
Synonyms
BAT
Description
Bile acid CoA:amino acid N-acyltransferase (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene is a liver enzyme that catalyzes the transfer of C24 bile acids from the acyl-CoA thioester to either glycine or taurine, the second step in the formation of bile acid-amino acid conjugates. The bile acid conjugates then act as a detergent in the gastrointestinal tract, which enhances lipid and fat-soluble vitamin absorption. Defects in this gene are a cause of familial hypercholanemia (FHCA). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Q14032 [Direct mapping] Bile acid-CoA:amino acid N-acyltransferase
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Enzymes ENZYME proteins Transferases Hydrolases MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
Q14032 [Direct mapping] Bile acid-CoA:amino acid N-acyltransferase
Show all
Enzymes ENZYME proteins Transferases Hydrolases MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Disease related genes Potential drug targets Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
