Expression of DENND4C in cancer - Summary

CANCER ATLAS

Gene description

DENN/MADD domain containing 4C

Protein class

Predicted intracellular proteins, Predicted membrane proteins

Protein evidence

Evidence at protein level

Colorectal cancer

Breast cancer

Prostate cancer

Lung cancer

Liver cancer

STAINING SUMMARY

HPA014917	HPA015096

GENE INFORMATION
Gene name	DENND4C (HGNC Symbol)
Synonyms	bA513M16.3, C9orf55, C9orf55B, FLJ20686
Description	DENN/MADD domain containing 4C (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	p22.1
Chromosome location (bp)	19230435 - 19373545
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000137145 (version 83.38)
Entrez gene	55667
UniProt
neXtProt
Antibodypedia	DENND4C antibodies

PROTEIN BROWSER

DENND4C-002	DENND4C-003	DENND4C-004	DENND4C-005	DENND4C-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DENND4C-002 ENSP00000369792 ENST00000380427	X6RAE7 [Direct mapping] DENN domain-containing protein 4C Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		881 aa 96.5 kDa	No	0
DENND4C-003 ENSP00000354301 ENST00000361024	X6R5W5 [Direct mapping] DENN domain-containing protein 4C Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		696 aa 76.8 kDa	No	0
DENND4C-004 ENSP00000369789 ENST00000380424	A0A0A0MRX3 [Direct mapping] DENN domain-containing protein 4C Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		353 aa 38 kDa	No	0
DENND4C-005 ENSP00000473565 ENST00000602925	R4GNB2 [Direct mapping] DENN domain-containing protein 4C; DENN/MADD domain containing 4C, isoform CRA_b Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0030904 [retromer complex] GO:0032593 [insulin-responsive compartment] GO:0032869 [cellular response to insulin stimulus] GO:0072659 [protein localization to plasma membrane] Show all	1909 aa 212.7 kDa	No	2
DENND4C-006 ENSP00000473469 ENST00000434457	R4GN35 [Direct mapping] DENN domain-containing protein 4C Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all		1958 aa 217.8 kDa	No	2